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Flucloxacillin

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Identification
Molecular formula
C19H17ClFN3O5S
CAS number
5250-39-5
IUPAC name
3,3-dimethyl-7-oxo-6-(2-phenoxypropanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Flucloxacillin is solid, commonly used in its sodium salt form for pharmaceutical preparations.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
241.00
Boiling point (Kelvin)
514.15
General information
Molecular weight
457.86g/mol
Molar mass
457.4860g/mol
Density
1.5480g/cm3
Appearence

Flucloxacillin typically appears as a white or almost white crystalline powder. It is practically insoluble in water but soluble in methanol and dimethylformamide.

Comment on solubility

Solubility of 3,3-Dimethyl-7-oxo-6-(2-phenoxypropanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C19H17ClFN3O5S)

The solubility of complex compounds such as 3,3-dimethyl-7-oxo-6-(2-phenoxypropanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid is influenced by several factors:

  • Molecular Structure: The presence of functional groups like phenoxy, carboxylic acid, and thioether can significantly affect solubility.
  • Polarity: Generally, polar compounds tend to be soluble in polar solvents. In this case, the carboxylic acid group may enhance solubility in water, while the phenoxy group might contribute to solubility in organic solvents.
  • Temperature: Solubility can increase with temperature for many compounds. Experimental data will help determine the optimal conditions.

As a complex molecule, estimating solubility can be challenging, but insights can be gained from empirical data. It is often necessary to test solubility under different conditions, and "like dissolves like" serves as a guiding principle in these evaluations.

In summary, the solubility of this compound is likely variable and dependent on numerous factors, necessitating detailed study for accurate characterization.

Interesting facts

Exploring 3,3-Dimethyl-7-Oxo-6-(2-Phenoxypropanoylamino)-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid

This unique compound is a fascinating example of a bicyclic structure that incorporates both sulfur and nitrogen, showcasing the complexity and diversity of organic chemistry. The compound's intricate design is structured around a cyclic framework, characterized by a thia (sulfur-containing) and azabicyclo (nitrogen-containing) configuration, making it a point of interest in the realm of medicinal chemistry.

Significance in Chemistry

The presence of multiple functional groups contributes to the compound’s potential biological activity. Some noteworthy aspects include:

  • Diverse Applications: Given its specific structure, this compound may exhibit antibacterial or antifungal properties, which could be useful in the development of new pharmaceuticals.
  • Complex Synthesis: The synthetic route to create this compound emphasizes the challenges chemists face when working with bicyclic structures, often requiring advanced techniques in organic synthesis.
  • Interdisciplinary Connections: Its unique composition is a point of study not only in organic chemistry but also in fields like pharmacology and medicinal chemistry, linking chemistry to real-world health applications.

Potential Research Avenues

Scientists are interested in compounds like this due to their potential for further exploration:

  • Mechanism of Action: Understanding how the compound interacts at the molecular level to exert any bioactivity can provide insights valuable in drug design.
  • Derivatives and Analogues: Chemists frequently study similar compounds to develop derivatives that enhance efficacy or reduce side effects.
  • Environmental Considerations: The synthesis and degradation pathways of such compounds may reveal important information about their environmental impact.

In summary, 3,3-dimethyl-7-oxo-6-(2-phenoxypropanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid illustrates a rich tapestry of science where organic chemistry meets medicinal applications, highlighting the importance of structural intricacies in the development of new chemical entities.

Synonyms
Pheneticillin;alpha-Phenoxyethylpenicillin
910024-37-2
MLS006011455
CHEMBL1622026
SCHEMBL17238870
DTXSID10859263
AKOS030241148
SMR004703257
NS00006393
3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid