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Cefoperazone

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Identification
Molecular formula
C25H27N9O8S3
CAS number
62893-19-0
IUPAC name
3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, cefoperazone is typically found in a solid state as a fine powder. It is used primarily as a sodium salt in the pharmaceutical industry.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
646.67g/mol
Molar mass
646.6650g/mol
Density
1.5238g/cm3
Appearence

Cefoperazone typically appears as a white to slight yellowish powder. It is a crystalline solid used in its salt forms for solubility in water.

Comment on solubility

Solubility of 3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of 3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C25H27N9O8S3) is influenced by several factors, reflecting its complex structure. Understanding its solubility is essential for both laboratory applications and theoretical studies. Here are key considerations:

  • Polar and Non-Polar Characteristics: The presence of multiple functional groups, including sulfonate and carboxylic acid moieties, suggests that this compound may exhibit high solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules can enhance solubility, particularly in aqueous environments.
  • Structural Complexity: The bicyclic structure combined with several substituents may lead to varying degrees of solubility depending on the specific solvent used.
  • Stability in Solution: It's essential to consider how the compound behaves in solution. Factors like pH may impact its solubility profile significantly.

In summary, while the chemical structure indicates favorable interactions with polar solvents, detailed studies are required to quantify its exact solubility in various media. As always, conducting practical solubility tests will provide the most accurate insights into its behavior in real-world applications.

Interesting facts

Interesting Facts about 3,3-Dimethyl-7-Oxo-6-[(2-Phenyl-2-Sulfo-Acetyl)amino]-4-Thia-1-Azabicyclo[3.2.0]heptane-2-Carboxylic Acid

This compound is a fascinating example of complex molecular architecture with potential implications in medicinal chemistry and pharmaceuticals. Notably, it features a bicyclic structure that is characteristic of many biologically active natural products. Here are some intriguing aspects:

  • Structural Complexity: The molecule showcases a blend of thiazole and sulfonyl functionalities, which are often found in biologically significant compounds. The thia (sulfur) and azabicyclo (nitrogen-containing) elements provide unique chemical reactivity and biological activity.
  • Potential Biological Applications: Compounds of this nature can serve as starting points for drug development, particularly in antibiotic or anti-inflammatory therapies. Their complex structure could influence how they interact with biological targets.
  • Mechanistic Insights: Researchers study compounds like this to understand their pharmacodynamics and pharmacokinetics, revealing how they are metabolized and how they exert their effects at a cellular level.
  • Analytical Challenges: The intricate nature of this compound also presents challenges in terms of synthesis and characterization. Techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography are often employed to elucidate the structure accurately.

With such a detailed molecular design, 3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid stands as a testament to the ingenuity found in chemistry. As noted by researchers, “The complexity of chemical structures often correlates with their biological activities, making them invaluable in scientific exploration.”

Overall, this compound not only enriches the field of chemical synthesis but also paves the way for new discoveries in pharmaceutical applications.

Synonyms
Sulbenicillin
alpha-sulfobenzylpenicillin
DTXSID40860408
58569-36-1
3,3-Dimethyl-7-oxo-6-[2-phenyl(sulfo)acetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid