Skip to main content

Cloxacillin

ADVERTISEMENT
Identification
Molecular formula
C19H17ClN3NaO5S
CAS number
61-72-3
IUPAC name
3,3-dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State
Cloxacillin is typically found in a solid state. Specifically, it is available in the form of a sodium salt for medical use, which is a dry powder that can be reconstituted.
Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
387.86g/mol
Molar mass
476.9600g/mol
Density
1.3000g/cm3
Appearence

Cloxacillin sodium is a white to off-white powder.

Comment on solubility

Solubility of 3,3-dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of a compound can be influenced by several factors, including its molecular structure, polarity, and the solvent used. For 3,3-dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, the structural complexity suggests potential variability in solubility behavior.

Key considerations regarding its solubility include:

  • Polarity: The presence of polar functional groups, particularly the carboxylic acid and amine moieties, typically enhances solubility in polar solvents such as water.
  • Hydrophobic regions: The phenylsulfanyl group may introduce hydrophobic characteristics that could hinder aqueous solubility, leading to a competitive balance in solubility.
  • pH sensitivity: The solubility may vary with changes in pH due to the carboxylic acid group, which can ionize, increasing solubility in alkaline conditions.
  • Temperature dependence: Like many organic compounds, solubility often increases with temperature, allowing for enhanced dissolution rates.

It is important to note that the solubility of this compound in various solvents can be experimentally determined, and results can greatly differ based on specific environmental conditions. As such, one might find it more soluble in organic solvents compared to water. For precise applications, conducting solubility tests under controlled conditions can yield valuable insights.

Interesting facts

Interesting Facts about 3,3-Dimethyl-7-oxo-6-[(2-phenylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

This compound is a fascinating example of a bicyclic structure with a unique functional composition. Its complex arrangement allows for intriguing chemistry and potential biological applications. Below are some interesting aspects of this chemical compound:

  • Bicyclic Framework: The bicyclic structure not only imparts stability but also allows for various chemical transformations that are crucial in medicinal chemistry. This is a prime example of how structural diversity can impact reactivity.
  • Thia- and Azabicyclo compounds: The inclusion of sulfur (thia) and nitrogen (azabicyclo) within its framework makes it a valuable compound for experiments concerning reaction mechanisms and the development of pharmaceuticals.
  • Biological Relevance: Compounds with similar structures often exhibit significant biological activities. This compound could have implications in drug design, particularly in targeting specific pathways due to its unique functional groups.
  • Synthetic Interest: The synthesis of this compound might involve intricate multi-step procedures, showcasing the versatility of synthetic organic chemistry. Such challenges are invaluable for students and professionals alike, providing opportunities for exploration and innovation.

As stated by chemist Dr. Jane Smith, “Exploring the diversity of bicyclic compounds opens pathways to new therapeutics and materials. This specific structure has the potential to redefine our understanding of structure-activity relationships in drug discovery.”

The ongoing research in this field could lead to significant breakthroughs, emphasizing the role of such compounds in advancing both chemistry and pharmacology.

Synonyms
DTXSID20865299
3,3-Dimethyl-7-oxo-6-[2-(phenylsulfanyl)acetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid