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Bromhexine hydrochloride

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Identification
Molecular formula
C16H21Cl3N
CAS number
611-75-6
IUPAC name
(3,4-dichlorophenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium;chloride
State
State

Bromhexine hydrochloride is typically in a solid state at room temperature, existing as a crystalline powder.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
252.00
Boiling point (Kelvin)
525.15
General information
Molecular weight
412.55g/mol
Molar mass
412.5540g/mol
Density
1.3743g/cm3
Appearence

Bromhexine hydrochloride appears as a white or almost white crystalline powder. It is odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of (3,4-dichlorophenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium; chloride

The solubility of the compound (3,4-dichlorophenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium; chloride can be intriguing due to its unique structure and the presence of various functional groups. This compound is typically a quaternary ammonium salt, which often exhibits the following solubility behavior:

  • Polar Solvents: Generally, quaternary ammonium salts are soluble in polar solvents, such as water and alcohols, due to their ionic nature.
  • Non-Polar Solvents: The presence of large hydrocarbon groups can lead to lower solubility in non-polar solvents like hexane or benzene.
  • Temperature Influence: Solubility may increase with temperature, as higher temperatures can promote the dissolution of ionic compounds.
  • pH Dependency: The solubility can also be dependent on pH, since the ionic state of the compound can change with varying acidity or basicity in solution.

Overall, one might observe that the solubility is enhanced in aqueous and polar environments, making it a compound that can easily engage with biological systems or undergo chemical reactions in such solvents. As quoted in solubility studies, "like dissolves like," reflects a critical principle to consider when predicting its behavior in different solvent systems.

Interesting facts

Interesting Facts about (3,4-Dichlorophenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium Chloride

The compound known as (3,4-dichlorophenyl)methyl-(1,7,7-trimethylnorbornan-2-yl)ammonium chloride belongs to a class of quaternary ammonium compounds, which are known for their wide array of applications in various fields, from pharmaceuticals to materials science. Here are some intriguing aspects of this compound:

  • Quaternary Ammonium Compounds: This compound is a quaternary ammonium salt, typically characterized by a positively charged nitrogen atom bonded to four organic groups. These salts are known for their antimicrobial properties and utility in disinfectants and surfactants.
  • Dichlorophenyl Moiety: The presence of the 3,4-dichlorophenyl group suggests that this compound may have significant biological activity. Chlorinated aromatic compounds often exhibit enhanced interactions with biological targets, making them useful in drug design and development.
  • Norbornane Structure: The norbornan-2-yl portion indicates a bicyclic structure that can influence the compound’s stereochemistry and conformational flexibility. The unique structure of norbornane plays a crucial role in its interactions and reactivity.
  • Applications: Compounds like this are not only of interest for their pharmacological properties but also for their potential use in materials chemistry. They can serve as surfactants, corrosion inhibitors, and in the formulation of agrochemicals.
  • Synthesis Challenges: The synthesis of complex organic molecules like this compound often involves multiple steps of functionalization and may require advanced techniques in organic synthesis, showcasing the intricate dance of chemical transformations in drug development.

In summary, this compound not only highlights the fascinating world of quaternary ammonium compounds but also embodies the intersection of organic synthesis, biological activity, and potential applications that excite scientists across disciplines. As one researcher once said, "The beauty of chemistry lies in its complexity and its ability to shape the world around us."

Synonyms
(+-)-endo-N-(3,4-Dichlorobenzyl)-2-bornanamine hydrochloride
22243-57-8
2-BORNANAMINE, N-(3,4-DICHLOROBENZYL)-, HYDROCHLORIDE, endo-(+-)-
RefChem:256674