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3,4-Dihydro-1H-1,3,4-benzotriazepine-2,5-dione

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Identification
Molecular formula
C8H7N3O2
CAS number
6164-63-0
IUPAC name
3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
497.00
Boiling point (Kelvin)
770.15
General information
Molecular weight
177.16g/mol
Molar mass
177.1610g/mol
Density
1.4780g/cm3
Appearence

3,4-Dihydro-1H-1,3,4-benzotriazepine-2,5-dione typically appears as a crystalline solid with a white to off-white color. The appearance might vary slightly due to impurities or specific synthesis routes.

Comment on solubility

Solubility of 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione

The solubility of 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione can be influenced by several factors, leading to interesting considerations:

  • Polarity: This compound exhibits a moderate level of polarity due to its heterocyclic structure, which can affect its interaction with solvents.
  • Solvent Interaction: It is generally more soluble in solvents such as ethanol and dimethyl sulfoxide (DMSO), while its solubility in water is limited.
  • Temperature Effects: Increased temperatures can enhance the solubility of the compound in organic solvents, a common behavior observed with many organic compounds.
  • Hydrogen Bonding: The presence of nitrogen atoms in the benzotriazepine structure may lead to hydrogen bonding, further impacting solubility in various solvents.

In summary, the solubility of 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione is non-uniform across different solvents, exhibiting a tendency for better solubility in polar organic solvents compared to water. As stated, "the nature of the solvent often dictates the solubility profile of a compound," making it essential to choose the correct medium for dissolving this particular chemical.

Interesting facts

Interesting Facts about 3,4-Dihydro-1H-1,3,4-benzotriazepine-2,5-dione

The compound 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione is quite fascinating due to its structural characteristics and potential applications. Here are some key points to consider:

  • Structural Complexity: This compound features a benzotriazepine core, characterized by a fusion of a benzene ring with a triazole, demonstrating the intricate nature of heterocyclic chemistry.
  • Medical Relevance: Due to its unique structure, 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione has been studied for its potential therapeutic effects, including its implications in areas such as psychiatry and neurology.
  • Derivative Variability: The ability to modify different parts of the benzotriazepine structure opens a realm of possibilities in creating derivatives that could exhibit diverse biological activities.
  • Reactions and Synthesis: This compound is often prepared through multi-step synthesis, which may involve condensation reactions, reflecting the challenges and creativity inherent in synthetic organic chemistry.

In the words of renowned chemist, Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” This resonates well with the exploration of compounds like 3,4-dihydro-1H-1,3,4-benzotriazepine-2,5-dione, as ongoing research may yield new insights and applications.

Overall, the study of this compound not only enriches our understanding of benzotriazepine derivatives but also exemplifies the intricate relationship between structure and function in medicinal chemistry.

Synonyms
3,4-Dihydro-1H-1,3,4-benzotriazepine-2,5-dione
18852-14-7
BRN 0746222
1,3,4-Benzotriazepine-1H-2,5-dione
1H-1,3,4-Benzotriazepine-2,5-dione, 3,4-dihydro-
DTXSID70172208
DTXCID6094699
2,3,4,5-tetrahydro-1h-1,3,4-benzotriazepine-2,5-dione
EN300-2008097