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3,4-Dihydroisoquinoline-2-carboxamidine sulfate

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Identification
Molecular formula
C10H14N2 · H2SO4
CAS number
N/A
IUPAC name
3,4-dihydro-1H-isoquinoline-2-carboxamidine;sulfuric acid
State
State

The compound is a solid at room temperature. It is often procured in its sulfate form which enhances its stability in storage and handling.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
252.31g/mol
Molar mass
252.3070g/mol
Density
1.2000g/cm3
Appearence

The compound is typically seen as a colorless to white crystalline powder. It is generally hygroscopic and can absorb moisture from the air.

Comment on solubility

Solubility of 3,4-dihydro-1H-isoquinoline-2-carboxamidine in Sulfuric Acid

The compound 3,4-dihydro-1H-isoquinoline-2-carboxamidine demonstrates notable solubility characteristics when interacting with sulfuric acid. In acidic environments, particularly with strong acids like sulfuric acid, solubility can exhibit remarkable behavior due to the compound's structure and functional groups.

  • Acid-Base Interaction: The presence of an amidine functional group can enhance solubility as it can engage in protonation, leading to improved dissolution in acidic solvents.
  • Polar Nature: The polar character of the compound contributes to its affinity for polar solvents, making sulfuric acid a suitable medium for solubilization.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature, facilitating greater interaction with the sulfuric acid.

In summary, the solubility of 3,4-dihydro-1H-isoquinoline-2-carboxamidine in sulfuric acid can be characterized as favorable, particularly due to its ability to interact through protonation with the acid. As always, the specifics of solubility can vary with concentration, temperature, and the presence of other solutes or solvent interactions.

Interesting facts

Interesting Facts About 3,4-Dihydro-1H-Isoquinoline-2-Carboxamidine; Sulfuric Acid

3,4-Dihydro-1H-isoquinoline-2-carboxamidine is a fascinating compound that belongs to the isoquinoline family, known for its presence in various natural products and biological systems. Here are some intriguing aspects of this compound:

  • Biological Significance: Compounds derived from isoquinoline structures are often found in a variety of biological activities, including antimicrobial, antiviral, and anticancer properties. This makes them of great interest in medicinal chemistry.
  • Role in Drug Development: Isoquinolines are frequently utilized as scaffolds for designing new pharmacological agents. The unique structural features of 3,4-dihydro-1H-isoquinoline-2-carboxamidine can offer novel pathways for therapeutic development.
  • Acid-Base Chemistry: The presence of sulfuric acid in this compound introduces a distinct acidic environment. Sulfuric acid is known for its strong dehydrating properties and acts as a catalyst in various chemical reactions, thereby influencing the stability and reactivity of the compound.
  • Research Potential: The combination of 3,4-dihydro-1H-isoquinoline-2-carboxamidine with sulfuric acid may pave the way for exploring new synthetic methodologies, revealing insights into the formation of complex organic molecules.

As a future chemist, exploring such compounds is both an exciting and crucial journey. Understanding their properties could lead to breakthroughs in various scientific fields, demonstrating the intricate connections between chemical structure and biological function. "Every molecule tells a story," and in the case of isoquinolines, it's a rich and diverse narrative waiting to be unraveled.

Synonyms
DEBRISOQUIN SULFATE
581-88-4
Declinax
Isocaramidine sulfate
Debrisoquin hemisulfate
Pasiron-T
Equitonil
Debrisoquin sulfate [USAN]
Debrisoquin sulphate
Ro 5-3307/1
EINECS 209-472-4
Declinax (TN)
NSC 139330
UNII-Q94064N9NW
DTXSID2047775
Q94064N9NW
NSC-139330
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1)
Debrisoquin sulfate (USAN)
3,4-Dihydro-2(1H)-isoquinolinecarboxamidine sulfate (2:1)
DEBRISOQUIN SULFATE [MI]
DTXCID2027755
CHEBI:50973
DEBRISOQUINE SULFATE [MART.]
1,2,3,4-Tetrahydro-isoquinoline-2-carboxamidine sulfate
RO-5-3307/1
3,4-DIHYDRO-2(1H)-ISOQUINOLINECARBOXAMIDINE SULPHATE (2:1)
DEBRISOQUINE SULFATE (MART.)
2(1H)-ISOQUINOLINECARBOXIMIDAMIDE, 3,4-DIHYDRO-, SULPHATE (2:1)
bis(3,4-dihydroisoquinoline-2(1H)-carboximidamide) sulfate
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate(2:1)
209-472-4
Debrisoquine sulfate
DEBRISOQUINSULFATE
Debrisoquine sulphate
Debrisoquin (Sulfate)
Debrisoquine Sulfate; Isocaramidine Sulfate
Ro 5-3307
NCGC00016513-01
CAS-581-88-4
3,4-dihydro-1H-isoquinoline-2-carboximidamide;sulfuric acid
Prestwick_690
SCHEMBL122316
CHEMBL1593558
CAYGYVYWRIHZCQ-UHFFFAOYSA-N
GLXC-06112
HMS1569K05
HMS2096K05
HMS3713K05
Tox21_110468
MFCD00153791
DEBRISOQUINE SULFATE [WHO-DD]
AKOS026751495
Tox21_110468_1
CCG-220372
NCGC00016513-05
Ro 5-33071
AS-16854
D03664
SR-01000872657
SR-01000872657-1
Q27122265
3,4-dihydroisoquinoline-2(1H)-carboximidamide hemisulfate