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3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide

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Identification
Molecular formula
C9H10N2O2
CAS number
3581-13-9
IUPAC name
3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide
State
State

At room temperature, 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide exists in a crystalline solid form. It is not volatile and remains stable under normal conditions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
178.21g/mol
Molar mass
178.2050g/mol
Density
1.2800g/cm3
Appearence

3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide typically presents as an off-white to pale yellow crystalline solid. It has a distinctive structure characteristic of substituted benzoxazines with an amide group adding to its chemical complexity.

Comment on solubility

Solubility of 3,4-Dihydro-2H-1,4-benzoxazine-2-carboxamide

The solubility of 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide can be influenced by several factors, and it exhibits unique characteristics that are worth noting:

  • Polarity: This compound is relatively polar due to the presence of the carboxamide functional group. This increases its ability to dissolve in polar solvents, such as water.
  • Temperature Sensitivity: The solubility may increase with temperature; thus, heating the solvent can enhance dissolution efficiency.
  • pH Dependence: As a carboxamide, its solubility can be pH-dependent. Under acidic or basic conditions, it could interact with the solvent differently, potentially affecting solubility.
  • Comparative Solubility: When compared to other related compounds, 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide may show notable differences based on the structure and functional groups present.

In summary, while specific solubility data for 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide may not be readily available, its structural characteristics suggest that it is likely soluble in polar solvents, with the aforementioned factors playing crucial roles in its overall behavior in solutions.

Interesting facts

Interesting Facts about 3,4-Dihydro-2H-1,4-benzoxazine-2-carboxamide

3,4-Dihydro-2H-1,4-benzoxazine-2-carboxamide is a fascinating compound with a diverse range of applications in chemistry and medicinal sciences. Here are some intriguing insights:

  • Structural Versatility: The compound features a unique fused ring system derived from benzene and oxazine, which contributes to its intriguing chemical behavior.
  • Biological Relevance: It has gained attention in the field of drug design due to its potential therapeutic properties, particularly in neuroprotection and anti-cancer activity.
  • Preparation Methods: The synthesis can often involve multi-step processes that require precise control of reaction conditions, showcasing the beauty of organic synthesis.
  • Dimensional Components: The compound contains both amide and carboxylic acid functionalities, allowing it to engage in hydrogen bonding, and enhancing its solubility in biological systems.
  • Research Focus: Recent studies have focused on its role as a precursor in the development of complex pharmaceuticals and as a ligand in coordination chemistry.

It's intriguing to note that compounds like 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide emphasize the intersection of structure and function in chemistry. As researchers continue to investigate its properties, we can expect to unlock more secrets hidden within its chemical architecture, further proving that even small changes in molecular structure can lead to significant variations in biological activity.


In the colorful world of chemical compounds, 3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide stands out as a prime example of the complex relationship between structure and function, opening doors to innovation in scientific research.

Synonyms
13582-93-9
3,4-Dihydro-2H-1,4-benzoxazine-2-carboxamide
BRN 0787073
2H-1,4-BENZOXAZINE-2-CARBOXAMIDE, 3,4-DIHYDRO-
853-248-4
3,4-dihydro-2h-4-benzoxazine-2-carboxamide
3,4-Dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide
CHEMBL1584522
MLS000569260
SCHEMBL1756748
SCHEMBL1756750
SCHEMBL6368347
DTXSID50929156
HMS2277B14
BDBM50576036
SBB056028
AKOS000204936
AKOS017269100
WAY-634605
NCGC00246103-01
SMR000154909
TS-02479
CS-0246735
EN300-34231
G30929
2H,3H,4H-benzo[e]1,4-oxazaperhydroine-2-carboxamide
3,4-Dihydro-2H-1,4-benzoxazine-2-carboximidic acid
Z57028529