Skip to main content

Coformycin

ADVERTISEMENT
Identification
Molecular formula
C10H15N5O7P2
CAS number
22021-88-1
IUPAC name
(3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl)methyl phosphono hydrogen phosphate
State
State

At room temperature, coformycin is in a solid state. It typically exhibits stability under normal conditions of temperature and pressure, and is often handled as a dry powder in laboratory settings.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
431.22g/mol
Molar mass
431.2200g/mol
Density
2.1600g/cm3
Appearence

Coformycin usually appears as a white to off-white powder in its solid form. The compound is generally crystalline in nature and may be sensitive to moisture when left in open air over time, potentially causing it to become more clumped or change in texture.

Comment on solubility

Solubility of (3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl)methyl phosphono hydrogen phosphate

The compound (3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl)methyl phosphono hydrogen phosphate, with the formula C10H15N5O7P2, presents unique solubility characteristics that are noteworthy for its applications in various fields.

In general, the solubility of a compound is influenced by several factors including:

  • Polarity: This compound contains both hydrophilic groups (like hydroxyl and phosphate) and hydrophobic components (such as the imidazole and tetrahydrofuran structures), leading to complex solubility behavior.
  • pH of the solution: The presence of acidic phosphate groups can affect its solubility in different pH conditions.
  • Temperature: Increased temperature typically leads to greater solubility for many organic compounds.

Many studies indicate that compounds with similar structural motifs often exhibit moderate to high solubility in polar solvents such as water or methanol but can be less soluble in non-polar solvents. For this specific compound, one might anticipate:

  • Good solubility in aqueous solutions due to its ionic nature.
  • Limited solubility in organic solvents unless specific structural interactions are facilitated.

Understanding the solubility of (3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl)methyl phosphono hydrogen phosphate is crucial for its effective utilization in drug formulation and delivery systems, where solubility can profoundly influence bioavailability and therapeutic effectiveness.

Interesting facts

Interesting Facts about (3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl)methyl phosphono hydrogen phosphate

This unique compound is a remarkable member of the purine and phosphono family, showcasing a structure that interlinks biological activity with synthetic chemistry. Here are some fascinating insights:

  • Biological Significance: The purine framework is pivotal in various biological processes, particularly in forming nucleotides, which are fundamental for nucleic acids like DNA and RNA.
  • Enzyme Inhibitor: Due to the presence of hydroxy and phosphono groups, this compound has been investigated for its potential to inhibit certain enzymes, making it a candidate for therapeutic applications.
  • Versatile Synthesis: Synthetic pathways leading to this compound often involve complex reactions that can yield various derivatives, enhancing its functional applications in drug design.
  • Research Implications: Studies around this compound could reveal insights into metabolic pathways and their implications in diseases, particularly in understanding cellular mechanisms.
  • Structure-Activity Relationship (SAR): The intricate arrangement of functional groups can significantly influence the compound's biological activity, making it ripe for SAR studies to advance medicinal chemistry.

In scientific discourse, this compound is sometimes considered a "chemical chameleon" due to its ability to potentially interact with multiple biological targets. As one researcher put it: "Compounds like this one redefine our understanding of molecular interactions in biological systems." Its role at the intersection of chemistry and medicine exemplifies the ongoing quest to harness chemical diversity for innovative solutions in healthcare.

Synonyms
SR-01000929984
SR-01000929984-1