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Haloperidol

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Identification
Molecular formula
C21H23ClFNO2
CAS number
52-86-8
IUPAC name
(3,4-dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone
State
State

At room temperature, Haloperidol exists as a solid. It is stable under standard conditions of use and storage, making it suitable for pharmaceutical formulations. It should be stored in a tightly closed container, away from light and moisture.

Melting point (Celsius)
167.50
Melting point (Kelvin)
440.65
Boiling point (Celsius)
537.80
Boiling point (Kelvin)
810.95
General information
Molecular weight
375.86g/mol
Molar mass
375.8640g/mol
Density
1.2279g/cm3
Appearence

The compound appears as a white to slightly off-white crystalline powder. It is generally crystalline in nature and may exhibit slight variations in shade due to factors such as purity and the presence of trace impurities.

Comment on solubility

Solubility of (3,4-dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone

The solubility of a compound plays a crucial role in understanding its potential applications and behavior in various environments. For the compound (3,4-dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone, several factors impact its solubility:

  • Polarity: The presence of methoxy and hydroxyl groups suggests a certain degree of polarity, which can influence solubility in polar solvents like water.
  • Functional Groups: The dimethylamino group typically increases solubility in polar environments due to its ability to engage in hydrogen bonding.
  • Molecular Weight: With a relatively high molecular weight, the solubility may not be as favorable as smaller molecular compounds.
  • Solvent Dependency: The compound may exhibit better solubility in organic solvents like ethanol or DMSO compared to water.

In summary, while (3,4-dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone may exhibit varying solubility depending on the solvent, it could be anticipated that it will demonstrate:

  • Increased solubility in polar organic solvents
  • Moderate solubility in water, reflecting its complex structure

Ultimately, detailed experimental data would be necessary to characterize its solubility behavior comprehensively.

Interesting facts

Interesting Facts about (3,4-Dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone

This complex compound boasts unique features that make it a point of interest in both synthetic organic chemistry and pharmaceutical sciences. Its structural intricacies open up numerous avenues for research and application. Here are some intriguing aspects:

  • Structural Diversity: The compound incorporates multiple functional groups, including methoxy groups, a hydroxyl group, and a dimethylamino group. This diversity can influence its reactivity and solvent interactions.
  • Biological Activity: Compounds with similar structures have been explored for their potential biological activities. They may exhibit properties ranging from anti-inflammatory to antitumor effects, making them suitable candidates for further pharmacological investigations.
  • Synthetic Challenge: The synthesis of this compound may pose challenges due to its intricate structure. Various methods, including multi-step synthesis and the use of protecting groups, may be required to achieve the desired final product.
  • Research Potential: Scientists are always on the lookout for novel compounds with unique structures. This compound's potential to act as a lead compound in drug discovery could open doors to new treatments and therapies.
  • Designing Analogues: The presence of different functional groups allows for the design of analogues with modified properties. Such variations can help researchers understand structure-activity relationships and enhance biological activities.

As highlighted by renowned chemists, "The beauty of organic chemistry lies in the diversity of structures and systems we can design." (3,4-Dimethoxyphenyl)-[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]methanone stands out as a testament to that beauty, showcasing the intricate dance between structure and function in the realm of chemical compounds.

Synonyms
AG-205/08032056