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3,4,5-Triiodobenzoic acid

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Identification
Molecular formula
C7H3I3O2
CAS number
88-82-4
IUPAC name
3,4,5-triiodobenzoic acid
State
State

At room temperature, 3,4,5-Triiodobenzoic acid is typically found in a solid state.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
398.60
Boiling point (Kelvin)
671.80
General information
Molecular weight
499.83g/mol
Molar mass
499.8280g/mol
Density
2.8660g/cm3
Appearence

3,4,5-Triiodobenzoic acid appears as a crystalline solid. It is typically white to off-white in color and can be found in a powdered form.

Comment on solubility

Solubility of 3,4,5-Triiodobenzoic Acid

3,4,5-Triiodobenzoic acid, with the chemical formula C7H4I3O2, exhibits interesting solubility properties influenced by its molecular structure and the presence of iodine atoms. Solubility can be affected by several factors, including temperature, pH, and the nature of the solvent.

Key Points on Solubility:

  • Polar versus Nonpolar Solvent: Being an aromatic carboxylic acid, 3,4,5-triiodobenzoic acid tends to dissolve better in polar solvents due to its carboxylic acid group.
  • Aqueous Solubility: Typically, carboxylic acids show limited solubility in water, and this compound is no exception due to the bulkiness of the iodine substituents, which can hinder the compounds' interactions with water molecules.
  • Organic Solvent Solubility: However, in organic solvents such as ethanol or methanol, its solubility is generally improved, providing a broader range of applications in organic chemistry.

In summary, while 3,4,5-triiodobenzoic acid has limited solubility in water, it is more soluble in organic solvents, making it useful in various chemical contexts. Understanding the solubility behavior of this compound is essential for its effective application in experimental and practical settings.

Interesting facts

Interesting Facts About 3,4,5-Triiodobenzoic Acid

3,4,5-Triiodobenzoic acid, often abbreviated as TIBA, is a fascinating organic compound recognized for its unique structural characteristics and diverse applications in the field of chemistry.

Chemical Structure

This compound features a benzoic acid core with three iodine atoms substituted at the 3rd, 4th, and 5th positions. The presence of multiple iodine atoms grants it several noteworthy properties:

  • Electronics: The iodine atoms significantly affect the electron distribution, enhancing the reactivity of the aromatic ring.
  • Stability: The compound demonstrates notable stability thanks to the aromatic system, making it suitable for various reactions.

Applications

TIBA has garnered attention in various scientific research areas:

  • Medical Research: It is often investigated for its potential roles in pharmaceuticals and treatments, particularly in hormone-related studies.
  • Analytical Chemistry: Its unique properties make it useful in chromatographic techniques for analyzing complex mixtures.
  • Material Science: TIBA's ability to modify surfaces is being explored for enhancing the properties of polymers and other materials.

Unique Features

Some unique aspects of 3,4,5-triiodobenzoic acid include:

  • It is a derivative of benzoic acid, illustrating how functionalization can alter compound properties.
  • The iodine-rich structure lends *antimicrobial properties*, contributing to its potential in health-related applications.
  • Environmental Impact: Research indicates that its derivatives can behave differently in biological systems, raising interest in eco-toxicological studies.

Interestingly, TIBA has also been noted for its role in studying **iodine metabolism** within living organisms. As chemistry students and scientists continue to explore the potential of this compound, we can expect its applications and significance to expand!

Synonyms
3,4,5-Triiodobenzoic acid
2338-20-7
BENZOIC ACID, 3,4,5-TRIIODO-
NSC 11811
EINECS 219-050-1
3,4,5-Triiodobenzoicacid
BRN 2264330
AI3-27443
NSC11811
3,5-Triiodobenzoic acid
WLN: QVR CI DI EI
Benzoic acid,4,5-triiodo-
3-09-00-01457 (Beilstein Handbook Reference)
3,4,5-Triiodo-benzoic acid
SCHEMBL122324
CHEMBL415511
DTXSID90177932
UCBKDZNMPMBJAB-UHFFFAOYSA-N
MFCD00016513
NSC-11811
AKOS015890301
FT70767
TS-09854
CS-0148760
NS00049422
EN300-171676
G29188
Z1269124794
InChI=1/C7H3I3O2/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2H,(H,11,12