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3,4,5-trimethylisoxazole

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Identification
Molecular formula
C6H9NO
CAS number
24803-69-0
IUPAC name
3,4,5-trimethylisoxazole
State
State
At room temperature, 3,4,5-trimethylisoxazole exists in a liquid state, displaying the typical characteristics of a low-viscosity fluid.
Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
138.50
Boiling point (Kelvin)
411.65
General information
Molecular weight
111.14g/mol
Molar mass
111.1440g/mol
Density
0.9465g/cm3
Appearence
3,4,5-Trimethylisoxazole is typically found as a colorless and transparent liquid. It may have a distinctive odor characteristic of isoxazoles, which are aromatic compounds.
Comment on solubility

Solubility of 3,4,5-trimethylisoxazole

3,4,5-trimethylisoxazole is an intriguing compound with notable solubility characteristics. The solubility of this compound can be influenced by several factors:

  • Polar vs. Non-Polar Solvents: 3,4,5-trimethylisoxazole tends to be more soluble in organic solvents such as ethanol and dichloromethane, owing to its non-polar characteristics.
  • Temperature Dependency: Like many organic compounds, its solubility may increase with temperature, making it essential to consider this factor during experimental applications.
  • Hydrogen Bonding: The presence of nitrogen and the isoxazole ring can undergo interactions that slightly enhance its solubility in polar solvents.

In summary, 3,4,5-trimethylisoxazole displays variable solubility, and its behavior in different solvents can be summarized as:

  1. Good solubility in non-polar organic solvents
  2. Moderate solubility in polar solvents
  3. Temperature can enhance solubility

Understanding the solubility profile of 3,4,5-trimethylisoxazole is crucial for its application in various fields, especially in organic synthesis and pharmaceuticals. Always consider the solvent choice for optimal results!

Interesting facts

Interesting Facts About 3,4,5-Trimethylisoxazole

3,4,5-Trimethylisoxazole is a fascinating organic compound that belongs to the family of isoxazoles, which are five-membered aromatic heterocycles containing nitrogen and oxygen atoms. Here are some intriguing aspects of this chemical:

  • Structural Significance: The presence of three methyl groups at the 3, 4, and 5 positions of the isoxazole ring contributes to the compound's unique characteristics and reactivity.
  • Biological Relevance: Compounds like 3,4,5-trimethylisoxazole have shown potential in pharmacological applications, including their roles as anti-inflammatory agents and in the treatment of neurodegenerative diseases.
  • Chemical Versatility: The versatile structure of 3,4,5-trimethylisoxazole makes it an interesting precursor in the synthesis of various pharmaceuticals and agrochemicals.
  • Research Potential: Ongoing research into isoxazole derivatives continues to unveil new reactions and applications, highlighting the compound's relevance in medicinal chemistry.
  • Historical Context: The isoxazole class of compounds has been utilized in the development of numerous drugs since the mid-20th century, showcasing their importance in drug discovery.

In addition, the interesting geometry and stability of the isoxazole ring allow for various reactions, making 3,4,5-trimethylisoxazole a subject of interest in synthetic organic chemistry. As researchers delve deeper into the properties and applications of this compound, it continues to reveal opportunities for innovation and advancement in chemical sciences.

Synonyms
3,4,5-Trimethylisoxazole
10557-82-1
Isoxazole, trimethyl-
Trimethylisoxazole
ISOXAZOLE, 3,4,5-TRIMETHYL-
trimethyl-1,2-oxazole
USAF CS-1340
3,4,5-trimethyl-1,2-oxazole
3,4,5-TRIMETHYL-ISOXAZOLE
Isoxazole,3,4,5-trimethyl-
O5ZX92B98S
3,4,5-TRIMETHYLOXAZOLE
BRN 0107040
UNII-O5ZX92B98S
ISOXAZOLE, TRIMETHY
SCHEMBL12486
4-27-00-00988 (Beilstein Handbook Reference)
SCHEMBL352211
SCHEMBL2093257
SCHEMBL3315330
SCHEMBL11629729
MGHKWBQZEBMFOH-UHFFFAOYSA-
DTXSID80902518
MGHKWBQZEBMFOH-UHFFFAOYSA-N
AKOS006275934
Q27285377
InChI=1/C6H9NO/c1-4-5(2)7-8-6(4)3/h1-3H3