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Aloe-emodin

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Identification
Molecular formula
C15H10O5
CAS number
481-72-1
IUPAC name
3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one
State
State

At room temperature, Aloe-emodin is a solid. It typically forms crystals which are vibrant in color, contributing to its frequent use as a biochemical marker.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
647.50
Boiling point (Kelvin)
920.65
General information
Molecular weight
270.24g/mol
Molar mass
270.2410g/mol
Density
1.4762g/cm3
Appearence

Aloe-emodin appears as an orange-red crystalline compound. It is typically found as a fine powder and is not soluble in cold water, which contributes to its recognized texture and appearance in its pure form.

Comment on solubility

Solubility of 3,4,6a,10-Tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one

The solubility of 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one is an intriguing aspect of its chemical behavior, which plays a significant role in its applications. Here are some key points to consider:

  • Polar Nature: Due to the presence of multiple hydroxyl (-OH) groups, the compound exhibits a certain degree of polarity, potentially enhancing its solubility in polar solvents.
  • Solvent Dependency: It is likely to be soluble in solvents such as water and alcohols, whereas its solubility may decrease in non-polar solvents like hexane or chloroform.
  • Hydrogen Bonding: The hydroxyl groups enable hydrogen bonding, which can facilitate interactions with solvent molecules, thereby aiding solubility.

In conclusion, while the solubility profile of 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one varies with the solvent used, its capacity for hydrogen bonding and polar nature suggests a tendency towards solubility in polar environments. As always, experimental validation is crucial for determining precise solubility characteristics.

Interesting facts

Interesting Facts about 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one

This unique chemical compound, known for its intricate structure, belongs to a class of molecules that has captured the interest of scientists studying natural products and organic reactions. It has remarkable features that highlight both its potential applications and the complexities of its chemical nature.

1. Structural Complexity

The compound's molecular structure includes a combination of fused ring systems, which contributes to its stability and reactivity. The presence of multiple hydroxy groups not only enhances its chemical properties but also increases its potential for interactions with biological systems.

2. Biological Significance

Research suggests that compounds similar to this one have been investigated for a variety of biological activities, including:

  • Antioxidant Properties: The hydroxy groups play a critical role in scavenging free radicals, thus offering protective benefits against oxidative stress.
  • Anticancer Activities: Some studies indicate that these compounds may exhibit properties that inhibit cancer cell proliferation and induce apoptosis.
  • Neuroprotective Effects: There is ongoing research into how this class of compounds can influence neurological health and provide protection against neurodegenerative diseases.

3. Synthetic Applications

From a synthetic chemistry standpoint, the compound serves as an intriguing target for organic synthesis. Its complex framework challenges chemists to develop efficient methodologies for its construction, often leading to the exploration of:

  • Multistep Synthesis: The intricate arrangement of functional groups necessitates innovative approaches to achieve the final product.
  • Catalytic Systems: Researchers are constantly exploring new catalytic pathways to improve yield and selectivity during synthesis.

4. Environmental Considerations

With a growing emphasis on sustainability, studies involving this compound may focus on green chemistry approaches to minimize waste and reduce harmful byproducts during its synthesis and application.

In summary, 3,4,6a,10-tetrahydroxy-6,7-dihydroindeno[2,1-c]chromen-9-one exemplifies the beauty of chemical diversity and holds promise not only in academic research but also in potential real-world applications.