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Nothofagin

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Identification
Molecular formula
C15H14O8
CAS number
529-53-9
IUPAC name
3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one
State
State

At room temperature, Nothofagin is a solid aromatic compound. It often occurs in the form of fine powder suitable for scientific investigation.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
332.27g/mol
Molar mass
332.3030g/mol
Density
1.6620g/cm3
Appearence

Nothofagin is typically found as a yellowish-white hydroscopic powder.

Comment on solubility

Solubility of 3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one

The compound 3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one (C15H14O8) exhibits unique solubility properties that are of interest in the realm of chemical science. Here are some important considerations:

  • Polarity: Due to the presence of multiple hydroxyl groups (-OH), this compound is expected to have significant polarity, which generally enhances solubility in polar solvents such as water.
  • Hydroxymethyl and Methoxy Groups: The hydroxymethyl (-CH2OH) and methoxy (-OCH3) substituents can further influence the solubility, potentially increasing its solubility in organic solvents. This dual behavior allows for versatile applications.
  • Hydrogen Bonding: The ability to form hydrogen bonds with adjacent molecules or solvents can lead to higher solubility, particularly in aqueous solutions.

In practical terms, this compound may exhibit:

  1. Moderate Solubility: Likely soluble in ethanol and methanol.
  2. Limited Solubility: Potentially less soluble in non-polar solvents like hexane.

Overall, while the solubility profile depends on various conditions, such as temperature and pH, understanding the interactions of its functional groups offers valuable insights into the compound's behavior in different environments. As with many complex organic compounds, experimentation remains key in determining the precise solubility characteristics.

Interesting facts

Exploring 3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one

This fascinating compound, known for its complex structure, represents an intriguing area of study within the realm of organic chemistry. Its multifaceted nature reveals several key aspects worth exploring:

  • Natural Product: This compound belongs to a class of molecules often derived from natural sources, showcasing how nature can synthesize compounds with intricate architectures.
  • Pharmacological Potential: Many complex organic molecules like this one exhibit potential medicinal properties. Researchers are keen on studying their effects, leading to the discovery of new therapeutics.
  • Chemical Stability: The presence of multiple hydroxyl groups contributes to unique chemical behavior, influencing reactivity and stability, thus making it a target for synthetic chemists.
  • Structure-Activity Relationship: Understanding how structural variations impact biological activity can provide insights into how similar compounds may function, a critical aspect of drug design.
  • Analytical Techniques: Characterizing such complex compounds often requires advanced techniques such as NMR spectroscopy and mass spectrometry, which are essential tools in the chemist's toolbox.

As scientists and students navigate the fascinating landscape of organic chemistry, compounds like this offer rich material for investigation, leading to potentially groundbreaking discoveries in both pharmacology and synthetic methods. The continued study of these intricate structures underscores the endless possibilities that lie within the world of chemical compounds, emphasizing the motto, "The more we learn, the more we realize how much there is to discover."


Synonyms
Bengenin
3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one
NSC383465
Corylopsin
Cuscutin;Corylopsin
Prestwick0_000811
Prestwick1_000811
Prestwick2_000811
Prestwick3_000811
BSPBio_000701
MLS006011420
Bergenin, Bergenin monohydrate
SCHEMBL893718
SPBio_002622
BPBio1_000773
CHEMBL1619590
CHEBI:91545
DTXSID40859392
YWJXCIXBAKGUKZ-UHFFFAOYSA-N
3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-one
BCP15931
CID 2356
BBL010129
STK801469
ZINC00000079
ZINC00389665
ZINC01303449
ZINC02048952
AKOS005613004
AC-8033
NSC-383465
SMP1_000100
NCGC00179471-01
LS-14297
SMR001550645
DB-051478
BRD-A15034104-002-03-6
Q27163378
3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano[3,2-c][2]benzopyran-6H-one
3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c][2]benzopyran-6-one
3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c][2]benzopyran-6(2H)-one
3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-one #
bergenin:pyrano[3,2-c][2]benzopyran-6(2h)-one,3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, [2r-(2,3,4,4a, 10b)]-,
Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, [2R-(2.alpha.,3.beta.,4.alpha.,4a.alpha.,10b.beta.)]-