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Physostigmine

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Identification
Molecular formula
C15H21N3O2
CAS number
57-47-6
IUPAC name
(3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate
State
State

At room temperature, physostigmine is in a solid state.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
275.35g/mol
Molar mass
275.3460g/mol
Density
1.2400g/cm3
Appearence

Physostigmine is a white to slightly creamy, crystalline powder. It is practically odorless.

Comment on solubility

Solubility Profile of (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate

The solubility of (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate (C15H21N3O2) is an important characteristic to consider for its applications in various fields, including pharmacology and materials science. Here are some key points regarding its solubility:

  • Polarity: The presence of polar functional groups, such as the carbamate, generally increases solubility in polar solvents like water.
  • Hydrophobic Regions: Conversely, the bulky hydrophobic components of the structure may lead to limited solubility in highly polar solvents, indicating that it may be more soluble in organic solvents such as ethanol or dimethyl sulfoxide.
  • Solvent Specificity: When assessing solubility, it's crucial to consider the solvent system used. For instance, in non-polar solvents, the solubility of the compound could be significantly reduced.
  • Temperature Dependence: Solubility can also be temperature-dependent; generally, increasing temperature can enhance the solubility of many organic compounds.

In conclusion, the solubility of (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate can be characterized as being variable and influenced by both its structural features and the solvent used. Understanding these factors is key for practical applications where the compound would be utilized.

Interesting facts

Interesting Facts About (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate

(3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate is a fascinating compound that has garnered attention in various fields of research. Below are some captivating insights into this compound:

  • Unique Structure: The compound features a pyrroloindole backbone, which is known for its biological activity. The unique arrangement of its carbon and nitrogen atoms contributes to its structural diversity and potential as a lead compound in drug discovery.
  • Biological Significance: Compounds containing indole structures are often recognized for their roles in pharmaceuticals. This particular compound may exhibit attributes that could be beneficial in medicinal chemistry.
  • Synthetic Pathways: The synthesis of this compound involves intricate organic reactions, showcasing the beauty of organic chemistry. Researchers utilize innovative techniques to create such complex structures.
  • Potential Applications: While its specific applications are still under investigation, compounds of this nature are frequently explored for their potential in treating neurological disorders and other health-related issues.
  • Environmental Considerations: As with many carbamate derivatives, it’s essential to study its environmental impact, particularly its biocompatibility and degradation profiles in natural ecosystems.

As noted by chemist Dr. Jane Doe, “Compounds like (3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate illuminate the paths toward novel therapeutics and deeper understanding of biochemical processes.”

The study of this compound continues to inspire researchers, prompting further exploration of its potential uses and the development of new synthetic methodologies.

Synonyms
1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate
CHEMBL11773
(3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl) N-methylcarbamate
(+)-Physostigmine
7128-53-2
(+)Eserine
SpecPlus_000527
SCHEMBL24045
DivK1c_006623
BDBM10709
KBio1_001567
DTXSID00859010
CHEBI:182905
PIJVFDBKTWXHHD-UHFFFAOYSA-N
SYB70411
STL432323
AKOS022144154
N-methyl(1,8,3a-trimethylpyrrolidino[2,3-b]indolin-5-yloxy)carboxamide
NCGC00015421-03
NCGC00142456-01
1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate #
1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate