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Nimustine

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Identification
Molecular formula
C9H13Cl2N3O5
CAS number
42471-28-3
IUPAC name
3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid
State
State

At room temperature, Nimustine is typically found as a solid. Due to its nature, it is handled under controlled conditions to prevent degradation.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
354.13g/mol
Molar mass
354.7420g/mol
Density
1.4200g/cm3
Appearence

Nimustine appears as a yellowish, crystalline powder. It is known for its sensitivity to light and, therefore, should be stored in dark conditions to preserve its integrity.

Comment on solubility

Solubility of 3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid

The solubility of 3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid is quite intriguing due to its unique chemical structure. When diagnosing its solubility properties, consider the following factors:

  • Polarity: The presence of polar functional groups, such as the carbamoyl and carboxylic acid moieties, may enhance its ability to dissolve in polar solvents like water.
  • Hydrogen Bonding: The carboxylic acid group can form hydrogen bonds, which may contribute to solubility in aqueous environments.
  • Organic Solvent Compatibility: Its structure also suggests potential solubility in various organic solvents, depending on the solvent's ability to interact with the compound.

However, it’s important to note that specific solubility data can vary based on several conditions. A few points to keep in mind include:

  • Temperature: Higher temperatures usually increase solubility.
  • pH Levels: The acidic nature of the compound may shift its solubility based on the pH of the solution.
  • Presence of Other Ions or Solutes: The solubility can be affected by the presence of competing ions or solutes.

To sum up, while 3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid exhibits potential for solubility in both polar and non-polar solvents, empirical testing is essential to determine exact solubility under varied conditions. As the adage goes, "the solution lies in the testing."

Interesting facts

Interesting Facts about 3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid

3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid is a complex compound that showcases the intricate world of organic chemistry. Here are some fascinating insights about this particular chemical:

  • Chemical Structure: The compound features a unique arrangement of functional groups, including nitroso, carbamoyl, and chloride, which contribute to its potential reactivity and interaction with biological systems.
  • Potential Applications: The presence of the nitroso group hints at possible uses in fields such as medicinal chemistry, where many nitroso compounds are investigated for their biological activity and potential therapeutic effects.
  • Toxicological Considerations: While compounds containing chloroethyl groups can possess cytotoxic properties, their mechanisms of action often warrant careful study. This compound's intricate structure could lead to a variety of biological responses, making it a candidate for toxicological research.
  • Related Compounds: This compound may bear resemblance to certain chemotherapeutic agents, often designed to target specific types of cancer cells. Its structural features might allow it to engage in similar interactions with cellular components.
  • Synthetic Pathways: Understanding how to synthesize this structure can provide insights into organic synthesis techniques, particularly those involving amine and carboxylic acid functional groups.

This compound serves as a reminder of the rich diversity found in organic chemistry and the potential it holds for research and application in various scientific domains.

Synonyms
13907-61-4
BENZOIC ACID, 3,5-BIS(3-(2-CHLOROETHYL)-3-NITROSOUREIDO)-
NSC 84955
BRN 2925833
3,5-Bis(3-(2-chloroethyl)-3-nitrosoureido)benzoic acid
DTXSID70160882
1,1'-(5-Carboxy-m-phenylene)bis(3-(2-chloroethyl)-3-nitrosourea)
Urea, 1,1'-(5-carboxy-m-phenylene)bis(3-(2-chloroethyl)-3-nitroso-
Benzoic acid, 3,5-bis[3-(2-chloroethyl)-3-nitrosoureido]-
DTXCID6083373
3,5-bis[[2-chloroethyl(nitroso)carbamoyl]amino]benzoic acid
NSC84955
NSC-84955
Benzoic acid,5-bis[3-(2-chloroethyl)-3-nitrosoureido]-