3,5-bis(mercapto)isothiazole-4-carboxamide

Identification

Molecular formula

C₄H₄N₂OS₃

CAS number

147769-58-4

IUPAC name

3,5-bis(sulfanyl)isothiazole-4-carboxamide

State

At room temperature, 3,5-bis(mercapto)isothiazole-4-carboxamide is typically a solid.

Melting point (Celsius)

204.10

Melting point (Kelvin)

477.30

Boiling point (Celsius)

349.30

Boiling point (Kelvin)

622.30

General information

Molecular weight

194.26g/mol

Molar mass

194.2600g/mol

Density

2.1305g/cm³

Appearence

The compound typically appears as a crystalline solid. It may present in different shades, often depending on purity and specific condition of appearance.

Comment on solubility

Solubility of 3,5-bis(sulfanyl)isothiazole-4-carboxamide

The solubility of 3,5-bis(sulfanyl)isothiazole-4-carboxamide, often referred to in chemical literature as a compound with intriguing characteristics, can be understood through various factors. Here are some key points regarding its solubility:

Polarity: The presence of functional groups, such as carboxamide and sulfanyl, affects its polarity. This may result in varying solubility in polar vs. non-polar solvents.
Solvent Interaction: The ability of this compound to dissolve in solvents can be influenced by hydrogen bonding, particularly due to the carboxamide group.
Temperature Sensitivity: Like many compounds, its solubility could change with temperature – often, higher temperatures can lead to increased solubility.
pH Dependence: The solubility may also be affected by pH levels, especially because carboxamide groups can engage in ionization under different pH conditions.

It is emphasized that the specific solubility of 3,5-bis(sulfanyl)isothiazole-4-carboxamide would require experimental data for definitive figures, but understanding these factors can help predict its behavior in various environments.

In summary, consider the unique interactions at play: “Solubility is not just a measure, but a dance between molecular structures and their environments.”

Interesting facts

Interesting Facts about 3,5-bis(sulfanyl)isothiazole-4-carboxamide

3,5-bis(sulfanyl)isothiazole-4-carboxamide, often referred to as a notable compound in thiazole chemistry, possesses some unique attributes that appeal to researchers across various fields. Here are several captivating insights:

Structural Significance: This compound features a distinctive isothiazole ring, which infuses it with properties critical in medicinal chemistry. The presence of sulfanyl groups enhances its potential for biological activity, making it a fascinating subject for exploration.
Potential Applications: Compounds in the isothiazole family have been recognized for their role as:

Antimicrobial agents
Anti-inflammatory substances
Pharmaceutical intermediates

Bioactivity Research: Studies have indicated that compounds similar to 3,5-bis(sulfanyl)isothiazole-4-carboxamide can exhibit significant biological activities. Researchers are keen on uncovering how modifications can lead to enhanced efficacy against various pathogens.
Synthetic Pathways: The synthesis of this compound involves intricate multi-step reactions, demonstrating the versatility of thiazole chemistry. Knowledge of diverse synthetic techniques is invaluable to chemists working on similar compounds.
Environmental Impact: As it is studied further, understanding the environmental implications of isothiazole derivatives remains crucial. Research into biodegradable pathways can improve their application in sustainable chemistry.

In conclusion, 3,5-bis(sulfanyl)isothiazole-4-carboxamide is more than just a chemical entity; it's a gateway to understanding complex biological interactions and the ongoing quest for novel therapeutic agents. As we continue to unveil the mysteries of this compound, its role in advancing modern chemistry and medicine remains a compelling narrative.