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3,5-Bis(trifluoromethyl)benzoic acid

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Identification
Molecular formula
C9H4F6O2
CAS number
445-00-1
IUPAC name
3,5-bis(trifluoromethyl)benzoic acid
State
State

At room temperature, 3,5-Bis(trifluoromethyl)benzoic acid is in a solid state. It is typically encountered as a crystalline solid, and due to its fluorinated groups, it may exhibit increased chemical stability compared to non-fluorinated benzoic acids.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
272.12g/mol
Molar mass
272.1230g/mol
Density
1.6100g/cm3
Appearence

3,5-Bis(trifluoromethyl)benzoic acid appears as a white to off-white crystalline solid, which may also be described as a powder. Its appearance is consistent with many organic acids that have aromatic components and fluorinated substituents.

Comment on solubility

Solubility of 3,5-bis(trifluoromethyl)benzoic acid

3,5-bis(trifluoromethyl)benzoic acid, with its unique structure containing multiple trifluoromethyl groups, exhibits interesting solubility behavior. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of trifluoromethyl groups contributes to the overall polarity of the molecule, making it less likely to dissolve in nonpolar solvents.
  • Acidic Character: As a carboxylic acid, 3,5-bis(trifluoromethyl)benzoic acid can form ionic species in the presence of water, which can enhance its solubility in polar solvents.
  • Solvent Interaction: The compound is more soluble in polar protic solvents, like water and alcohols, compared to apolar solvents.

In summary, the solubility of 3,5-bis(trifluoromethyl)benzoic acid is primarily dictated by the balance between its polar and nonpolar attributes. It tends to show higher solubility in polar environments, especially when compared to more hydrophobic compounds. Understanding these solubility characteristics is crucial for its applications in various chemical processes.

Interesting facts

Interesting Facts about 3,5-bis(trifluoromethyl)benzoic acid

3,5-bis(trifluoromethyl)benzoic acid is a fascinating compound with unique properties and applications that make it noteworthy in the field of chemistry. Here are some key points that highlight its significance:

  • Fluorinated Chemical: This compound is notable for its trifluoromethyl groups, which significantly enhance its chemical stability and lipophilicity. These characteristics often lead to improved performance in various applications.
  • Applications in Organic Synthesis: It serves as an important building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals, where fluorinated compounds are often sought after for their efficacy.
  • Environmental Impact: The trifluoromethyl group's properties influence the compound's behavior in biological systems, making it an interesting subject for studies in environmental chemistry.
  • Research Interest: Researchers are attracted to 3,5-bis(trifluoromethyl)benzoic acid for its potential in creating novel materials and for studying chemical reactions involving fluorinated compounds.
  • Importance in Material Science: Its unique properties lend themselves to applications in the development of advanced materials, including polymers and coatings that require enhanced performance characteristics such as chemical resistance.

In conclusion, 3,5-bis(trifluoromethyl)benzoic acid is more than just a chemical compound; it represents a bridge to various scientific disciplines, showcasing the intricate relationship between structure and function in the world of chemistry. As one researcher aptly put it, "Understanding the nuances of such compounds opens doors to innovation."

Synonyms
3,5-Bis(trifluoromethyl)benzoic acid
725-89-3
3,5-di(Trifluoromethyl)benzoic acid
BENZOIC ACID, 3,5-BIS(TRIFLUOROMETHYL)-
Bis(3,5-trifluoromethyl)benzoic acid
EINECS 211-970-1
NSC 88282
BRN 2058600
NN52L84T3A
NSC-88282
3,5-bis(trifluoromethyl) benzoic acid
UNII-NN52L84T3A
HVFQJWGYVXKLTE-UHFFFAOYSA-
TORCETRAPIB METABOLITE M1
DTXSID20222808
3,5-Di-(trifluoromethyl) benzoic acid
DTXCID10145299
211-970-1
hvfqjwgyvxklte-uhfffaoysa-n
inchi=1/c9h4f6o2/c10-8(11,12)5-1-4(7(16)17)2-6(3-5)9(13,14)15/h1-3h,(h,16,17)
MFCD00000388
NSC88282
Maybridge1_003411
SCHEMBL503980
CHEMBL3728871
HMS551D01
3,5-bistrifluoromethylbenzoic acid
3,5-bis-trifluoromethyl-benzoic acid
3,5-bis trifluoro methyl benzoic acid
3,5-bis(trifluoromethyl)-benzoic acid
3,5-bis-(trifluoromethyl)benzoic acid
AKOS000120436
AB00127
AC-3901
CCG-240220
CS-W012544
PS-7386
3,5-bis-(trifluoromethyl)-benzoic acid
SY016218
DB-055654
3,5-Bis(trifluoromethyl)benzoic acid, 98%
B1420
NS00042067
EN300-17196
D70169
Z56899078
F0001-1846