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Chloropyrazinecarbonitrile

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Identification
Molecular formula
C6H6ClN7O
CAS number
57101-11-8
IUPAC name
3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide
State
State
At room temperature, the compound is in a solid state, typically presented as a crystalline powder or compact solid mass.
Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
457.00
Boiling point (Kelvin)
730.15
General information
Molecular weight
213.59g/mol
Molar mass
213.5910g/mol
Density
1.7125g/cm3
Appearence

The compound is typically a yellow crystalline solid. It appears as a fine yellow powder that can be used in various industrial and chemical applications.

Comment on solubility

Solubility of 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide

The solubility of 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide is influenced by various factors, including temperature, polarity, and the presence of other solutes. This compound is largely characterized by the following solubility characteristics:

  • Polarity: The presence of multiple amino groups and a carboxamide group suggests that the compound is polar, which typically enhances solubility in polar solvents such as water.
  • Hydrogen Bonding: The capacity to form hydrogen bonds with water molecules can contribute significantly to its solubility. The amino and carboxamide groups can engage in *strong hydrogen bonding*, facilitating the dissolution process.
  • Temperature Effects: As with many organic compounds, increasing temperature may improve the solubility of this compound in aqueous solutions, as it can promote greater interaction between solute and solvent molecules.
  • Solvent Variability: While water is a likely solvent, the compound may also have varying solubilities in other solvents. Solubility in non-polar solvents is expected to be low due to its polar nature.

In summary, the solubility of 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide is primarily determined by its polar functional groups and the ability to form hydrogen bonds, making it relatively soluble in water and likely sparingly soluble in non-polar solvents. Understanding these solubility characteristics is essential for its application in various chemical processes and formulations.

Interesting facts

Interesting Facts about 3,5-Diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide

This fascinating compound belongs to the class of pyrazine derivatives, which have garnered significant interest in various fields of chemistry due to their unique structural properties and functionalities. Here are some noteworthy points about this compound:

  • Biological Significance: Compounds like this one have been researched for their potential use in pharmaceuticals, particularly for their antitumor and antimicrobial activities.
  • Structural Complexity: The presence of multiple amino groups contributes to the compound's reactivity and ability to participate in various chemical reactions, making it a valuable intermediate in organic synthesis.
  • Chlorination Impact: The chloro substituent in this compound can significantly affect its chemical behavior, enhancing its biological activity or altering its solubility profiles.
  • Analytical Applications: Due to its unique structure, it can be used as a probe in analytical chemistry for studying reactions involving nucleophiles.

As a chemistry student or a scientist, one might appreciate the potential applications of this compound. For instance, it could serve as a key building block in the synthesis of larger complex molecules. Further research into this compound could lead to the development of novel drugs or materials, illustrating how intricate chemical structures can have profound implications in scientific advancements.

In the words of a prominent chemist, "The beauty of chemistry lies in the interplay between structure and function; understanding one leads to insights about the other." This mantra rings true for compounds like 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide, setting a path for future exploration and discovery.

Synonyms
AMILORIDE
2609-46-3
Amipramidin
Guanamprazin
Guanamprazine
Amilorida
Amipramizid
Amiloridum
Amyloride
3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
Amiclaran
Amiloridum [INN-Latin]
Amilorida [INN-Spanish]
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide
N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid
CCRIS 6545
UNII-7DZO8EB0Z3
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
EINECS 220-024-7
7DZO8EB0Z3
CHEBI:2639
DTXSID9043853
DTXCID7023853
Amiloridum (INN-Latin)
Amilorida (INN-Spanish)
3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide
Amilorid
3,5-diamino-N-(amino(imino)methyl)-6-chloropyrazine-2-carboxamide
C03DB01
220-024-7
Midamor
Amipramizide
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
Amiloride (INN)
3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide
MK-870
137053-86-2
CHEMBL945
N-amidino-3,5-diamino-6-chloro-2-pyrazinecarboxamide
NCGC00015089-08
AMILORIDE [INN]
Amiloride [INN:BAN]
Amiclaran (TN)
CAS-2609-46-3
AmilorideHCl
Amikal (Hydrochloride dihydrate)
Midamor (Hydrochloride dihydrate)
MK-870 (Hydrochloride dihydrate)
Amipramidin, Midamor
3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride
Spectrum_000034
Tocris-0890
1f5l
AMILORIDE [MI]
Prestwick0_000007
Prestwick1_000007
Prestwick2_000007
Prestwick3_000007
Spectrum2_000118
Spectrum3_000293
Spectrum4_000132
Spectrum5_000776
AMILORIDE [VANDF]
Lopac-A-7410
AMILORIDE [WHO-DD]
Lopac0_000111
SCHEMBL27562
BSPBio_000013
BSPBio_001572
BSPBio_001826
KBioGR_000292
KBioGR_000544
KBioSS_000292
KBioSS_000394
MLS001060798
BIDD:GT0466
DivK1c_000182
SPBio_000136
SPBio_001934
BPBio1_000015
GTPL2421
BCBcMAP01_000101
BDBM16173
KBio1_000182
KBio2_000292
KBio2_000394
KBio2_002860
KBio2_002962
KBio2_005428
KBio2_005530
KBio3_000583
KBio3_000584
KBio3_001326
NINDS_000182
Bio1_000359
Bio1_000848
Bio1_001337
Bio2_000292
Bio2_000772
GLXC-06741
HMS1791O14
HMS1989O14
HMS2089H05
HMS2213E05
HMS3355K04
BCP16815
HY-B0285
Tox21_110080
BBL028157
STL373007
AKOS015961348
Tox21_110080_1
CCG-204206
DB00594
SB74937
SDCCGSBI-0050099.P005
IDI1_000182
IDI1_034042
NCGC00015089-01
NCGC00015089-02
NCGC00015089-03
NCGC00015089-04
NCGC00015089-05
NCGC00015089-06
NCGC00015089-07
NCGC00015089-09
NCGC00015089-11
NCGC00015089-12
NCGC00015089-13
NCGC00015089-14
NCGC00015089-15
NCGC00015089-16
NCGC00015089-17
NCGC00015089-24
NCGC00024443-02
NCGC00024443-05
NCGC00024443-06
NCGC00024443-07
NCGC00024443-09
AC-13631
LS-13128
SMR000486264
(3,5-Diamino-6-chloropyrazinoyl)guanidine
SBI-0050099.P004
DB-343790
N-amidino-3,5-diamino-6-chloropyrazinamide
AB00053415
NS00002250
C06821
D07447
EN300-149459
AB00053415-24
AB00053415-25
AB00053415_26
AB00053415_27
AB00053415_28
Q419995
BRD-K97181089-003-02-3
BRD-K97181089-003-22-1
BRD-K97181089-003-23-9
BRD-K97181089-003-24-7
BRD-K97181089-310-03-0
BRD-K97181089-310-06-3
N-amidino 3,5-diamino-6-chloro-2-pyrazinecarboxamide
F2173-0531
N-(3,5-Diamino-6-chloro-pyrazine-2-carbonyl)-guanidine
3,5-diamino-N-carbamimidoyl-6-chloro-pyrazine-2-carboxamide
3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride