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N-(3-(trifluoromethyl)phenyl)-3,5-dibromo-2-hydroxybenzamide

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Identification
Molecular formula
C14H8Br2F3NO2
CAS number
Not available
IUPAC name
3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.20
Boiling point (Celsius)
445.50
Boiling point (Kelvin)
718.70
General information
Molecular weight
454.93g/mol
Molar mass
454.9330g/mol
Density
1.7468g/cm3
Appearence

This compound is generally a solid and appears as a crystalline substance. The color and specific characteristics can vary, but it is typically a white to off-white powder.

Comment on solubility

Solubility of 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide

The solubility of 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide in various solvents can be influenced by several factors, including its structure and functional groups. Here are some insights into its solubility characteristics:

  • Polar solvents: Compounds with hydroxyl groups tend to exhibit increased solubility in polar solvents such as water and alcohols due to hydrogen bonding. Therefore, this compound may exhibit moderate solubility in water.
  • Non-polar solvents: Due to the presence of the trifluoromethyl group and aromatic rings, 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide may show greater solubility in non-polar solvents such as hexane or toluene.
  • Temperature effects: Like many organic compounds, solubility can vary with temperature. An increase in temperature often enhances solubility for many solid compounds.
  • pH impact: The ionization of the hydroxyl group may also result in varying solubility at different pH levels, which can alter the compound's interaction with solvents.

In summary, while the solubility profile of this compound can be complex, its structural features suggest a duality where it may be soluble in both polar and non-polar environments under appropriate conditions. As always, actual solubility measurements are essential for precise applications and usage.

Interesting facts

Interesting Facts about 3,5-Dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide

This compound, known as a member of the benzamide family, presents an intriguing profile both in structure and potential applications. Its unique composition includes two bromine atoms and a trifluoromethyl group, which significantly influence its chemical behavior.

Chemical Characteristics

  • Diverse Functional Groups: The presence of hydroxyl and bromine functionalities suggests potential for participating in a variety of chemical reactions, enhancing its versatility.
  • Trifluoromethyl Group: This group is known for enhancing metabolic stability and lipophilicity, making compounds with it often more potent in biological applications.

Applications and Relevance

This benzamide derivative's structural features make it a candidate for studying:

  • Pharmaceutical Research: Compounds like this are often explored for their potential therapeutic properties, especially as anti-inflammatory or anticancer agents due to their ability to interact with specific biological targets.
  • Material Science: The incorporation of bromine can also enhance the flame retardant properties in polymers, making it significant for safety materials development.

In Conclusion

As scientists delve deeper into the properties and behaviors of compounds like 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide, they uncover layers of complexity that offer insights into design strategies for new drugs and materials. Its unique configuration exemplifies how modifying molecular structures can lead to significant advancements in multiple scientific fields.

Synonyms
FLUOROSALAN
Flusalan
4776-06-1
Fluorsalan
Vancide FP
Fluorosalan [USAN]
Flusalan [INN]
Caswell No. 290
3,5-Dibromo-3'-(trifluoromethyl)salicylanilide
Flusalanum [INN-Latin]
80OFG3WPYD
3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide
Flusalan (INN)
NSC-166520
Fluorosalan (USAN)
DTXSID0041985
FLUOROSALAN [MI]
EINECS 225-322-0
UNII-80OFG3WPYD
EPA Pesticide Chemical Code 027601
NSC 166520
BRN 1155294
DTXCID8021985
3,5-Dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide
Benzamide, 3,5-dibromo-2-hydroxy-N-(3-(trifluoromethyl)phenyl)-
3,5-Dibromo-3'-(triflouromethyl)salicylanilide
3,5-Dibromo-alpha,alpha,alpha-trifluoro-m-salicylotoluidide
m-Salicylotoluidide, 3,5-dibromo-alpha,alpha,alpha-trifluoro-
Flusalanum (INN-Latin)
3,5-Dibromo-.alpha.,.alpha.,.alpha.-trifluoro-m-salicylotoluidide
Benzamide, 3,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]-
FLUOROSALAN [INCI]
Fluorophene
3,5-Dibromo-3'-trifluoromethylsalicylanilide
CHEMBL283552
NSC166520
NCGC00181143-01
Flusalanum
CAS-4776-06-1
SCHEMBL374268
CHEBI:135715
EAA77606
Tox21_112749
Tox21_302424
BDBM50027790
NCGC00181143-02
NCGC00255963-01
NCI60_001302
NS00046637
D04222
3,.alpha.,.alpha.-trifluoro-m-salicylotoluidide
SR-01000944883
SR-01000944883-1
Q27269166
3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide
Benzamide,5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]-
m-Salicylotoluidide,5-dibromo-.alpha.,.alpha.,.alpha.-trifluoro-
3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide(fluorophen)
Benzamide, 3, {5-dibromo-2-hydroxy-N-[3-(trifluoromethyl)phenyl]-}
m-Salicylotoluidide, 3,5-dibromo-.alpha.,.alpha., .alpha.-trifluoro-