Skip to main content

Bromadiolone

ADVERTISEMENT
Identification
Molecular formula
C13H9Br2NO2
CAS number
10383-40-3
IUPAC name
3,5-dibromo-2-hydroxy-N-phenyl-benzamide
State
State

At room temperature, 3,5-dibromo-2-hydroxy-N-phenyl-benzamide is typically a solid.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
710.00
Boiling point (Kelvin)
983.15
General information
Molecular weight
387.04g/mol
Molar mass
387.0410g/mol
Density
1.6269g/cm3
Appearence

3,5-dibromo-2-hydroxy-N-phenyl-benzamide typically appears as a solid with a crystalline structure. Its exact nature can vary depending on the specific derivative and purity, but it generally exhibits a white to light tan color.

Comment on solubility

Solubility of 3,5-Dibromo-2-hydroxy-N-phenyl-benzamide

The solubility of 3,5-dibromo-2-hydroxy-N-phenyl-benzamide can be influenced by several factors given its unique structural features. This compound includes a hydroxy group, which typically enhances solubility in polar solvents due to its ability to form hydrogen bonds. Additionally, the presence of bromine atoms may alter the hydrophobic characteristics of the molecule.

Key Points Regarding Solubility:

  • Polar Solvents: The hydroxy group suggests that this compound is likely to exhibit increased solubility in polar solvents such as water and alcohols.
  • Non-Polar Solvents: Conversely, the aromatic rings and bromine substitutions can impact solubility in non-polar or less-polar solvents, potentially reducing the overall solubility.
  • pH Dependence: The solubility may also be affected by the pH of the solvent, especially considering the hydroxy group’s ability to participate in acid-base reactions.

Overall, while the hydroxy group lends to increased solubility in aqueous environments, the bromine substitutions and aromatic character may create a complex balancing act that needs to be considered. As stated in the literature, “Understanding the interplay of functional groups is crucial for predicting solubility in various solvents.” Thus, experimental determination in specific solvents is recommended for precise solubility assessments.

Interesting facts

Interesting Facts about 3,5-Dibromo-2-hydroxy-N-phenyl-benzamide

3,5-Dibromo-2-hydroxy-N-phenyl-benzamide, commonly referred to in the realm of organic chemistry for its unique structure and properties, is a compound that exhibits fascinating characteristics:

  • Substituted Aromatic Compound: This compound is notable for its aromatic rings and multiple bromine substituents, which can significantly impact its reactivity and stability. The presence of bromine enhances its electrophilic character, making it a target for various chemical reactions.
  • Biological Relevance: Compounds featuring the benzamide structure, particularly those with hydroxyl groups, are often explored for their biological activities. Research indicates potential anti-inflammatory and antimicrobial properties, highlighting their importance in medicinal chemistry.
  • Importance in Material Science: The unique properties of dibrominated compounds like this one have implications in material science, specifically in developing polymers and dyes. With their intense color and stability, such compounds are valuable in creating pigments.
  • Role in Synthesis: 3,5-Dibromo-2-hydroxy-N-phenyl-benzamide serves as an important intermediate in organic synthesis. Its functional groups allow chemists to use it in cross-coupling reactions and other transformations.
  • Environmental Impact: The study of brominated compounds has gained attention due to their potential environmental effects. However, understanding their chemistry is crucial for developing safer alternatives and remediation strategies.

As a chemical student or scientist, it is essential to appreciate the multiple applications of compounds like 3,5-dibromo-2-hydroxy-N-phenyl-benzamide in fields ranging from pharmaceuticals to materials science. Furthermore, the exploration of such compounds aids in advancing our understanding of complex organic reactions.

Synonyms
METABROMSALAN
2577-72-2
3,5-Dibromosalicylanilide
Tempasept III
Metabromsalanum
3,5-Dibromosalicylide
NSC-526280
Caswell No. 289
Metabromsalan [USAN:INN]
Metabromsalanum [INN-Latin]
Salicylanilide, 3,5-dibromo-
EINECS 219-933-1
Benzamide, 3,5-dibromo-2-hydroxy-N-phenyl-
EPA Pesticide Chemical Code 077405
NSC 526280
BRN 2130998
UNII-8Q21Y09R21
Metabromsalan (USAN)
8Q21Y09R21
METABROMSALAN [INN]
METABROMSALAN [USAN]
METABROMSALAN [MART.]
DTXSID3042132
4-12-00-00907 (Beilstein Handbook Reference)
NSC526280
Metabromsalanum (INN-Latin)
METABROMSALAN (MART.)
DTXCID1022132
Salicylanilide, 3,5-dibromo-(8CI)
219-933-1
METABROMSALON
3,5-dibromo-2-hydroxy-N-phenylbenzamide
SCHEMBL1162534
CHEMBL1801800
YALKQBRWLMDVSA-UHFFFAOYSA-N
BDBM50468092
AKOS034527323
Benzamide,5-dibromo-2-hydroxy-N-phenyl-
3,5-Dibromo-2-hydroxy-N-phenyl-benzamide
NS00027961
D04950
EN300-1267200
Q27270878
Z68084788