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3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide

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Identification
Molecular formula
C12H13Br2NO3
CAS number
1234567-89-0
IUPAC name
3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide
State
State

At room temperature, this compound is typically a solid, owing to the presence of multiple bromine atoms which increase its molar mass and intermolecular forces.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
520.00
Boiling point (Kelvin)
793.15
General information
Molecular weight
393.97g/mol
Molar mass
393.9710g/mol
Density
2.1000g/cm3
Appearence

The compound typically appears as a crystalline solid. Its color may vary between white to off-white depending on the purity and specific crystalline form.

Comment on solubility

Solubility of 3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide

The solubility of 3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide can be influenced by various factors due to its complex structure. As a result of its unique functional groups, it may exhibit differing solubilities in various solvents:

  • Polar Solvents: Given the presence of the hydroxy (-OH) group, this compound may show increased solubility in polar solvents such as water and ethanol.
  • Non-Polar Solvents: The hydrophobic bromine atoms and the benzamide structure could render it more soluble in non-polar organic solvents like dichloromethane or chloroform.
  • Influence of Tetrahydrofuran: The tetrahydrofuran ring may also enhance solubility in certain organic solvents due to its ability to participate in solvation interactions.

It is essential to note that the specific solubility can also be affected by temperature, concentration, and the presence of other solute or solvent molecules in the environment. Therefore, empirical testing is crucial to accurately determine the solubility profile of this compound, as one might observe:

  1. The potential for solvate formation, which can alter the solubility characteristics.
  2. The influence of pH on the ionization of the hydroxyl and amide groups.

In summary, understanding the solubility of 3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide requires a comprehensive approach that considers both its chemical structure and the surrounding conditions. As the old saying goes, "Like dissolves like," emphasizing the importance of matching solvent properties to the compound’s characteristics for optimal solubility.

Interesting facts

Interesting Facts about 3,5-Dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide

This compound, 3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide, belongs to a class of chemicals that showcases the fascinating interplay between organic synthesis and medicinal chemistry. Here are some intriguing points:

  • Versatility in Synthesis: The incorporation of the tetrahydrofuran moiety adds a unique structural complexity, which can enhance the compound's biological activity and its interactions with various biomolecules.
  • Biological Activity: Compounds like this are often explored for their potential pharmacological properties. The bromine substituents can affect the compound's activity, making it potent against certain biological targets.
  • Hydroxyl Group Influence: The presence of a hydroxyl group (-OH) can significantly influence the compound's solubility and reactivity, which is crucial for drug design and development.
  • Environmental Significance: Understanding compounds with halogen functionalities is important for environmental chemistry, particularly in the study of their degradation pathways and potential ecological impacts.
  • Research Potential: This compound could serve as a scaffold for further modification to create a library of derivatives, each with distinct biological properties, making it a valuable compound in drug discovery efforts.

In summary, 3,5-dibromo-2-hydroxy-N-(tetrahydrofuran-2-ylmethyl)benzamide is not just a complex organic molecule; it represents the potential for new discoveries in the realms of medicinal chemistry and environmental science. As researchers continue to explore such compounds, they may uncover valuable insights that could lead to advancements in health and sustainability.

Synonyms
FURSALAN
15686-77-8
Fursalan [USAN:INN]
UNII-FY5QK5G88T
FY5QK5G88T
Fursalan (USAN)
FURSALAN [USAN]
FURSALAN [INN]
3,5-Dibromo-N-(tetrahydrofurfuryl)salicylamide
Benzamide, 3,5-dibromo-2-hydroxy-N-((tetrahydro-2-furanyl)methyl)-
3,5-dibromo-2-hydroxy-N-(oxolan-2-ylmethyl)benzamide
MLS006011529
SCHEMBL2109033
CHEMBL2104685
DTXSID90864618
AKOS034026349
SMR002529486
NS00122275
D04280
SR-01000945155
SR-01000945155-1
Q27278278
Z27766018
3,5-dibromo-2-hydroxy-N-[(oxolan-2-yl)methyl]benzamide