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3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide

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Identification
Molecular formula
C13H8Br3NOS
CAS number
N/A
IUPAC name
3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide
State
State

At room temperature, 3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide is typically found in a solid state. Like many organic solids, it is structured as fine crystalline particles.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
466.98g/mol
Molar mass
466.9780g/mol
Density
2.5100g/cm3
Appearence

3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide typically appears as a solid crystalline powder that may range in color from white to off-white or pale yellow. The compound is typically odorless.

Comment on solubility

Solubility of 3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide

The solubility of 3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide in various solvents can present unique challenges due to its complex structure. The presence of both bromine atoms and a sulfanyl group can influence its solubility in multiple ways:

  • Polar Solvents: This compound is likely to exhibit limited solubility in polar solvents, such as water, due to its large non-polar aromatic component and halogens.
  • Non-Polar Solvents: Conversely, it may have enhanced solubility in non-polar organic solvents (e.g., chloroform, benzene) where the hydrophobic interactions can be more favorable.
  • Effect of Temperature: The solubility is also expected to vary with temperature, as increased thermal energy can disrupt solute-solvent interactions.
  • pH Dependence: The solubility may be affected by the pH of the solution, particularly because the amide group can participate in hydrogen bonding.

In summary, the solubility of 3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide is conditional and depends greatly on the solvent and environmental conditions. As with many compounds containing halogens and sulfur functionalities, predicting solubility can require careful consideration of both chemical structure and solvent properties.

Interesting facts

Interesting Facts about 3,5-Dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide

3,5-Dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide is a fascinating compound that exemplifies the intricate relationships found within organic chemistry. Here are some noteworthy insights into this compound:

  • Multi-functional Groups: This compound contains multiple functional groups, including bromine substituents and a sulfanyl group, making it a candidate for diverse chemical reactions. The presence of these groups often influences its reactivity and potential applications.
  • Antimicrobial Activity: Compounds with bromine atoms are frequently studied for their biological activity, especially in antimicrobial research. It's common for aromatic brominated compounds to exhibit significant interactions with microbial cells.
  • Synthesis Challenges: The synthesis of such a compound can pose challenges due to steric hindrance and the regioselectivity of bromination. Chemists often utilize specific catalysts or reaction conditions to achieve the desired product.
  • Importance in Pharmaceutical Development: The sulfanyl group in this compound can play a crucial role in drug discovery. Studies suggest that compounds like this may be explored for their potential therapeutic effects, particularly in oncology and infectious disease research.
  • Environmental Impact: It's important to consider the environmental implications of using brominated compounds. Research on the environmental persistence and toxicity of such compounds is essential for responsible chemical use.

In conclusion, 3,5-dibromo-N-(4-bromophenyl)-2-sulfanyl-benzamide serves as an exemplary research subject in contemporary organic chemistry. Its multifaceted properties open avenues for further exploration and innovation.

Synonyms
THIOSALAN
TIOSALAN
15686-78-9
Thiosalan [USAN]
3,5-dibromo-N-(4-bromophenyl)-2-sulfanylbenzamide
Tiosalan [INN]
18778VU19U
Benzamide, 3,5-dibromo-N-(4-bromophenyl)-2-mercapto-
3,4',5-Tribromo-2-mercaptobenzanilide
3,5-Dibromo-N-(4-bromophenyl)-2-mercaptobenzamide
thio-salan
UNII-18778VU19U
Thiosalan (USAN/INN)
SCHEMBL2112176
CHEMBL2107581
DTXSID90166149
NS00124085
D06110
Q27251978