Skip to main content

3,5-Dichloropyridine

ADVERTISEMENT
Identification
Molecular formula
C5H3Cl2N
CAS number
2457-48-1
IUPAC name
3,5-dichloropyridine
State
State
At room temperature, 3,5-dichloropyridine is typically a liquid, which can take on a transparent to yellowish hue, depending on its purity and the presence of any impurities.
Melting point (Celsius)
3.50
Melting point (Kelvin)
276.65
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
146.99g/mol
Molar mass
146.9920g/mol
Density
1.4110g/cm3
Appearence
3,5-Dichloropyridine is typically a colorless to yellow liquid. It is often used in chemical synthesis and may exhibit a slightly pungent odor characteristic of halogenated pyridines.
Comment on solubility

Solubility of 3,5-Dichloropyridine

3,5-Dichloropyridine, with the chemical formula C5H3Cl2N, exhibits notable solubility characteristics that are essential for various applications. Here are some key points regarding its solubility:

  • Polar Nature: Due to the presence of the nitrogen atom and electronegative chlorine atoms, 3,5-dichloropyridine has a polar character, which generally enhances its solubility in polar solvents.
  • Solvent Compatibility: It is primarily soluble in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO). This implies its usefulness in organic synthesis and chemical reactions.
  • Limited Water Solubility: While 3,5-dichloropyridine can exhibit some solubility in water due to its polar groups, it is generally considered to be poorly soluble in water, which may limit its application in aqueous environments.
  • Concentration Factors: The solubility may also vary with temperature and concentration, making it crucial to consider these factors when dissolving the compound for experimental use.

In conclusion, the solubility of 3,5-dichloropyridine is influenced by its structural properties and the choice of solvent. Its polar characteristics allow for good solubility in various organic solvents, while its limited water solubility poses certain challenges for applications involving water.

Interesting facts

Interesting Facts about 3,5-Dichloropyridine

3,5-Dichloropyridine is a fascinating compound belonging to the pyridine family, which is characterized by its nitrogen-containing ring structure. As a member of the chlorinated pyridines, it holds significant importance in both agricultural and pharmaceutical chemistry.

Key Highlights:

  • Versatile Intermediate: This compound is a valuable intermediate in the synthesis of a variety of agrochemicals and pharmaceuticals. It serves as a building block for the production of herbicides and insecticides.
  • Role in Drug Development: Researchers often utilize 3,5-dichloropyridine in the design of novel drugs. Its unique structure allows for modifications that may enhance efficacy against various diseases.
  • Environmental Impact: Understanding the behavior and degradation of such chlorinated compounds is crucial, as environmental chemists study their potential impact on ecosystems.

The pyridine ring itself contributes to the compound's reactivity, making it an excellent candidate for various chemical reactions. Its two chlorine substituents at the 3 and 5 positions introduce unique electronic properties, enhancing its reactivity and changing its chemical pathways.

Quotes from the Field:

As noted by one prominent chemist, "The elegance of how simple modifications in pyridine derivatives can lead to significant functional changes in biological activity is always a point of intrigue in our research."

In summary, 3,5-dichloropyridine exemplifies the intersection of synthetic chemistry and practical application, showcasing the importance of understanding chemical structures in driving innovation in both agriculture and medicine.

Synonyms
3,5-DICHLOROPYRIDINE
Pyridine, 3,5-dichloro-
CCRIS 1719
EINECS 219-537-9
D9K92ASQ4D
NSC 60546
BRN 0001973
NSC-60546
DTXSID60179307
5-20-05-00417 (Beilstein Handbook Reference)
Pyridine, 3,5dichloro
DTXCID50101798
219-537-9
inchi=1/c5h3cl2n/c6-4-1-5(7)3-8-2-4/h1-3
wpghpgaufijvjf-uhfffaoysa-n
2457-47-8
MFCD00006376
NSC 60546;
NSC60546
3.5-Dichloropyridine
3,5-dichloro-pyridine
UNII-D9K92ASQ4D
WLN: T6NJ CG EG
3,5-Dichloropyridine, 98%
SCHEMBL197638
BCP05054
STL570178
AKOS005256831
AB00743
CS-W016343
FG-0510
HY-W015627
AC-24483
DB-023847
A5045
D0411
NS00021926
EN300-84253