LY-293284 | Solubility of Things

Identification

Molecular formula

C₂₂H₂₆N₄O

CAS number

161506-70-3

IUPAC name

3,5-dimethyl-N-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)pyrazole-1-carboxamide

State

This compound is a crystalline solid at room temperature.

Melting point (Celsius)

210.00

Melting point (Kelvin)

483.15

Boiling point (Celsius)

494.15

Boiling point (Kelvin)

767.30

General information

Molecular weight

358.47g/mol

Molar mass

358.4670g/mol

Density

1.3200g/cm³

Appearence

This compound typically appears as a colorless crystalline solid under standard laboratory conditions.

Comment on solubility

Solubility of 3,5-dimethyl-N-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)pyrazole-1-carboxamide

The solubility of this complex compound can be quite intriguing due to its unique molecular structure. Factors that significantly influence the solubility include:

Molecular Interactions: The presence of functional groups can lead to hydrogen bonding, dipole-dipole interactions, and even van der Waals force, which may increase solubility in polar solvents.
Polarity: The compound features regions that may vary from polar to non-polar; therefore, it may exhibit differing solubility properties in various solvents.
pH Sensitivity: If the compound has acidic or basic functional groups, its solubility might change with pH levels, often showing increased solubility in ionized forms.
Temperature Dependency: Solubility can also be temperature-dependent, with certain compounds being more soluble at higher temperatures.

In practice, one might observe that:

In polar solvents like ethanol or water, the solubility could be favorable due to potential hydrogen bonding.
In non-polar solvents such as hexane, the solubility may be significantly lower due to unfavorable interactions.

As a result, the solubility of 3,5-dimethyl-N-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)pyrazole-1-carboxamide is likely to be quite variable depending on these factors, making empirical tests crucial for determining its practical application in various scenarios.

Interesting facts

Interesting Facts about 3,5-Dimethyl-N-(7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl)pyrazole-1-carboxamide

This compound is a remarkable member of the pyrazole family, known for its diverse applications in medicinal chemistry and drug discovery. Let's delve into some fascinating aspects of this compound:

Complex Structure: The compound features a multi-ring structure that includes an indole and quinoline framework, which is often associated with biological activity and the potential for interacting with various biological targets.
Pharmacological Potential: Compounds similar to this one have been studied for their ability to act as modulators in various biological pathways. They may exhibit effects such as anti-inflammatory, anti-cancer, or neuroprotective properties.
Synthetic Pathways: The synthesis of this compound highlights the intricacies of organic chemistry, utilizing various techniques such as cyclization and carboxamidation, showcasing the creativity required in the lab.
Application in Drug Design: The unique chemical properties and potential bioactivity make it a valuable compound for designing new pharmaceuticals. Researchers often explore derivatives of such compounds to enhance their efficacy.

As a chemist, one cannot help but be intrigued by the potential of such compounds to contribute to advancements in medicine. The intricate interplay of its chemical structure and biological activity can lead to significant breakthroughs in treatments for various conditions.

"The beauty of chemistry lies in its ability to unite seemingly disparate elements into a cohesive, functional whole." This quote resonates particularly well when considering compounds like this one, where the complexity may hold the key to new discoveries.