Phenylbutazone | Solubility of Things

Identification

Molecular formula

C₁₉H₂₀N₂O₂

CAS number

50-33-9

IUPAC name

3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide

State

At room temperature, phenylbutazone is in a solid state. It is usually handled as a powder or tablet, both of which should be stored in a cool, dry place to maintain stability and efficacy.

Melting point (Celsius)

105.50

Melting point (Kelvin)

378.65

Boiling point (Celsius)

527.10

Boiling point (Kelvin)

800.25

General information

Molecular weight

308.37g/mol

Molar mass

308.3650g/mol

Density

1.2800g/cm³

Appearence

Phenylbutazone is a white to pale yellow crystalline powder. It is odorless and tasteless. The compound is often provided in the form of tablets or injectable solutions for medicinal purposes. When in solid form, it presents a fine and uniform consistency.

Comment on solubility

Solubility of 3,5-Dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide

The solubility of 3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide can be quite complex and is influenced by various factors. Here are some key points to consider:

Polarity: The presence of both polar and non-polar functional groups plays a critical role in determining the solubility of this compound in various solvents.
Solvent Interaction: Its solubility may vary significantly in different solvents:
- Water: Limited solubility due to hydrophobic character.
- Organic solvents: More soluble in organic solvents like ethanol or acetone, which can interact favorably with its structure.
Temperature: Higher temperatures can often increase solubility for many compounds; thus, elevated temperatures may enhance the solubility of ^3,5-dioxo-^1,2-diphenyl-^{pyrazolidine-4}-carboxamide.
pH Level: The solubility can also be affected by the pH of the solution, particularly if the compound can exist in different ionization states.

In conclusion, the solubility of 3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide can be described as solvent-dependent, and one must consider multiple aspects to accurately assess its solubility profile. As with many chemical compounds, understanding the interaction between the compound and its environment is key to predicting its solubility behavior.

Interesting facts

Interesting Facts about 3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide

3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide is a fascinating compound with a rich history in medicinal chemistry. This molecule is a member of the pyrazolidine family, which is known for its unique structural properties and biological activities.

Key Highlights:

Pharmacological Significance: This compound has attracted attention for its potential use as a pharmaceutical agent. Research suggests that it may exhibit anti-inflammatory and analgesic properties, which could be beneficial in treating various health conditions.
Structural Intrigue: The presence of multiple carbonyl groups within its structure contributes to its reactivity and interaction with biological systems, making it an interesting subject of study for medicinal chemists.
Synthetic Pathways: The synthesis of this compound often involves multi-step organic reactions that highlight the complexity and creativity of modern synthetic organic chemistry.
Applications in Research: 3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide is frequently used as a scaffold in drug design, where researchers modify its structure to enhance biological activity and reduce toxicity.

In conclusion, the compound 3,5-dioxo-1,2-diphenyl-pyrazolidine-4-carboxamide is not only a subject of significant interest due to its potential medicinal properties but also serves as an excellent example of the intricate relationships between molecular structure and biological function. As research continues, it may pave the way for new therapeutic avenues in the field of medicine.

Synonyms

KIS82D1KFH

1,2-DIPHENYL-4-CARBAMOYL-3,5-PYRAZOLIDINEDIONE

UNII-KIS82D1KFH

3,5-Dioxo-1,2-diphenyl-4-pyrazolidinecarboxamide

4-Pyrazolidinecarboxamide, 3,5-dioxo-1,2-diphenyl-

6126-32-5