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3,5-Diphenyl-1,2,4-triazole

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Identification
Molecular formula
C14H11N3
CAS number
129-26-8
IUPAC name
3,5-diphenyl-1H-1,2,4-triazole
State
State

At room temperature, 3,5-Diphenyl-1,2,4-triazole is in a solid state. It is stable and typically does not react readily with atmospheric components.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
381.00
Boiling point (Kelvin)
654.15
General information
Molecular weight
221.26g/mol
Molar mass
221.2580g/mol
Density
1.2385g/cm3
Appearence

3,5-Diphenyl-1,2,4-triazole typically appears as a white to off-white crystalline solid. Its appearance can vary based on the crystal size and purity. The crystalline nature reflects its ordered internal structure.

Comment on solubility

Solubility of 3,5-diphenyl-1H-1,2,4-triazole

3,5-diphenyl-1H-1,2,4-triazole, a unique organic compound, exhibits intriguing solubility characteristics that can significantly influence its application in various fields such as pharmaceuticals and agrochemicals. Understanding its solubility is essential for determining how it interacts in different environments.

Key Points of Solubility:

  • Polarity: Its structure, which contains aromatic rings, contributes to a degree of non-polarity, possibly leading to low solubility in polar solvents such as water.
  • Organic Solvents: It is generally more soluble in organic solvents like ethanol, acetone, and dichloromethane, making these solvents preferable for applications requiring dissolution.
  • Temperature Dependence: Solubility may be affected by temperature changes, where higher temperatures can increase solubility in organic solvents.

In summary, while 3,5-diphenyl-1H-1,2,4-triazole shows limited solubility in water, it readily dissolves in various organic solvents, making it versatile for solvent-based applications. The understanding of its solubility profile is essential for effective formulation and utilization in scientific research and practical applications.

Interesting facts

Interesting Facts about 3,5-Diphenyl-1H-1,2,4-triazole

3,5-Diphenyl-1H-1,2,4-triazole is a fascinating compound that belongs to the class of triazoles, which are five-membered heterocyclic compounds featuring nitrogen atoms in the ring. This particular compound has garnered attention in various fields due to its unique properties and potential applications.

Key Characteristics:

  • Pharmaceutical Applications: Its structural characteristics make it an important scaffold in drug discovery, particularly in the development of antifungal and anti-cancer agents.
  • Coordination Chemistry: 3,5-Diphenyl-1H-1,2,4-triazole acts as a ligand, bonding with metal ions, which can lead to the formation of various coordination complexes with interesting properties.
  • Biological Relevance: The compound has been studied for its ability to inhibit specific enzymes, highlighting its potential as a therapeutic agent.

Interesting Facts:

  • Triazole compounds are known for their efficacy against a wide range of pathogens.
  • The diphenyl substitution pattern enhances the compound's stability and solubility, making it suitable for experimental applications.
  • "The incorporation of nitrogen heterocycles into drug design is a powerful strategy in medicinal chemistry," says many chemists focused on pharmaceutical research.
  • This compound is also used in material science for research into new coordination polymers and as a building block for inorganic frameworks.

In summary, 3,5-diphenyl-1H-1,2,4-triazole is more than just a chemical structure; it represents a significant intersection of chemistry, biology, and material science, making it a valuable compound in research and development.

Synonyms
3,5-Diphenyl-4H-1,2,4-triazole
2039-06-7
3,5-Diphenyl-1H-1,2,4-triazole
3,5-Diphenyl-s-triazole
3,5-Diphenyl-1,2,4-triazole
1H-1,2,4-TRIAZOLE, 3,5-DIPHENYL-
s-Triazole, 3,5-diphenyl-
CHEMBL280106
3,5-diphenyl-4H-[1,2,4]triazole
1H-1,2,4-Triazole,3,5-diphenyl
MFCD00188356
WV4QRC6HBM
YSWG247
SCHEMBL384952
KPKQWXGFEKRQQA-UHFFFAOYSA-
3,5-DPT
DTXSID70174323
BDBM50518739
STK326454
1H-3,5-Diphenyl-1,2,4-triazole
AKOS002732988
AKOS003646246
3,5-Diphenyl-4H-1,2,4-triazole #
4H-1,2,4-triazole, 3,5-diphenyl-
AS-75894
DB-240789
CS-0156377
D94929
EN300-107143
Z1695709418
InChI=1/C14H11N3/c1-3-7-11(8-4-1)13-15-14(17-16-13)12-9-5-2-6-10-12/h1-10H,(H,15,16,17)