Aloe-emodin-8-glycoside | Solubility of Things

Identification

Molecular formula

C₂₂H₂₀O₁₀

CAS number

481-72-1

IUPAC name

3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]anthracene-2-carboxylic acid

State

At room temperature, Aloe-emodin-8-glycoside exists in a solid-state. It maintains its solid form under typical atmospheric conditions, and does not transition to other states (liquid or gas) unless subjected to extreme temperatures.

Melting point (Celsius)

223.00

Melting point (Kelvin)

496.15

Boiling point (Celsius)

707.00

Boiling point (Kelvin)

980.15

General information

Molecular weight

432.37g/mol

Molar mass

432.3730g/mol

Density

1.5610g/cm³

Appearence

Aloe-emodin-8-glycoside is typically a yellow-orange crystalline solid. It is derived from the anthraquinone aloe-emodin, which occurs naturally in Aloe species. The compound can be isolated as an off-yellow powder that has a bitter taste.

Comment on solubility

Solubility of 3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]anthracene-2-carboxylic acid

The solubility of 3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]anthracene-2-carboxylic acid (C₂₂H₂₀O₁₀) is influenced by its complex structure and the presence of multiple hydroxyl groups. These hydroxyl (-OH) functional groups enhance the compound's ability to interact with water, often resulting in increased solubility. Key points to consider include:

Hydrophilicity: The abundant hydroxyl groups suggest a high potential for hydrogen bonding with water molecules.
Polarity: The overall polarity of the molecule can significantly affect its solubility in polar solvents like water, as opposed to nonpolar solvents.
Temperature Dependency: Solubility can also be temperature-dependent, typically increasing with higher temperatures.

In conclusion, while the intricate polyhydroxylated structure of this compound suggests a favorable solubility profile in polar solvents, the exact solubility in water or other solvents would need to be tested experimentally to provide definitive insights. Overall, compounds with similar characteristics often exhibit notable solubility in aqueous environments due to their ability to form hydrogen bonds and engage in dipole-dipole interactions.

Interesting facts

Interesting Facts about 3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]anthracene-2-carboxylic acid

This fascinating compound is a member of the anthraquinone family, characterized by its rich array of hydroxyl groups, contributing to both its functional potential and its biological significance. Here are some intriguing aspects:

Natural Sources: This compound is often derived from various natural extracts and has garnered interest for its potential health benefits, particularly in traditional medicinal practices.
Biological Activity: Compounds of this type exhibit a range of biological activities, including antioxidant and anti-inflammatory properties, raising interest in pharmacological research.
Structural Complexity: Its intricate structure includes multiple hydroxyl groups and a dioxo functionality, highlighting how complex organic molecules can have profound properties arising from their unique arrangements of atoms.
Synthetic Utilization: The synthesis of such compounds often requires advanced organic chemistry techniques, showcasing the versatility and creativity of chemists in building complex architectures.
Potential Applications: Given its structural features, this compound may be explored in drug development, specifically in cancer therapeutics, due to its ability to modulate biological pathways within cells.

In summary, 3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2S,3S,4S,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]anthracene-2-carboxylic acid serves as a key example of how molecular structure impacts function in biological systems, making it a subject of ongoing research and interest.