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Naringenin

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Identification
Molecular formula
C15H12O5
CAS number
480-41-1
IUPAC name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one
State
State

Naringenin is a solid at room temperature.

Melting point (Celsius)
251.00
Melting point (Kelvin)
524.15
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
272.25g/mol
Molar mass
272.2530g/mol
Density
1.3610g/cm3
Appearence

Naringenin is typically found as a colorless crystalline solid. It can form a white to pale-yellow powder when isolated and purified.

Comment on solubility

Solubility of 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one

The compound 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one, with the chemical formula C15H12O5, exhibits diverse solubility characteristics that make it particularly interesting in various chemical contexts.

In general, the solubility of this compound can be influenced by several key factors:

  • Polarity: Strong polar hydroxyl (–OH) groups can enhance solubility in polar solvents, particularly water.
  • Hydrophobic interactions: The presence of aromatic rings and hydrocarbon chains may limit solubility in polar solvents.
  • Solvent choice: Common solvents such as ethanol or methanol may dissolve the compound adequately due to their balanced polarity.
  • Temperature: Higher temperatures typically increase solubility for many organic compounds, potentially making this compound more soluble at elevated temperatures.

As a result, it is suggested that the solubility of this compound is moderate in water but may improve in organic solvents. It can be summarized that:

  • The compound is likely soluble in ethanol and methanol.
  • It may exhibit limited solubility in nonpolar solvents such as hexane.

This intriguing balance of hydrophilic and hydrophobic properties adds to the compound's versatility for various applications in scientific research and pharmaceuticals.

Interesting facts

Interesting Facts About 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one

This fascinating compound, often referred to in scientific literature for its rich structural complexity, belongs to the flavonoid family, which are well-known for their diverse biological activities. Here are several intriguing points about this particular flavonoid:

Biological Significance

  • Antioxidant Properties: Compounds like this one are known for their ability to neutralize free radicals in the body, potentially reducing oxidative stress and contributing to overall health.
  • Aromatic Characteristics: The presence of hydroxyphenyl groups enhances the compound's interaction with biological systems, influencing its antioxidant capacity and cellular activity.
  • Anti-inflammatory Effects: Research indicates that flavonoids can modulate inflammatory pathways, making them a subject of interest in studies targeting chronic inflammation.

Chemical Structure Insights

The intricate structure of this compound features multiple hydroxyl (-OH) groups that not only boost solubility in biological fluids but also enhance its reactivity, drawing considerable attention in organic chemistry:

  • Chromen-4-one Core: This characteristic core is a hallmark of many bioactive compounds, highlighting the significance of chroman rings in pharmacology.
  • Substitutions: The specific substitutions at various positions lead to distinct chemical behaviors, granting the compound unique resonance properties.

Applications and Research

Ongoing research is investigating various applications of this compound:

  • Nutraceutical Development: Given its potential health benefits, scientists are exploring its use in dietary supplements.
  • Pharmaceutical Formulations: The compound may serve as a template for developing new drugs targeting specific diseases, especially those related to oxidative stress.

In summary, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one is not just a molecule; it is a promising candidate for numerous scientific explorations and therapeutic advancements that could pave the way for innovative health solutions. As with many flavonoids, understanding its full potential could contribute profoundly to both chemistry and biomedicine.