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Kaempferol

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Identification
Molecular formula
C15H10O6
CAS number
520-18-3
IUPAC name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one
State
State

Solid at room temperature.

Melting point (Celsius)
276.00
Melting point (Kelvin)
549.15
Boiling point (Celsius)
760.00
Boiling point (Kelvin)
1 033.15
General information
Molecular weight
286.24g/mol
Molar mass
286.2360g/mol
Density
1.6510g/cm3
Appearence

Kaempferol is a yellow crystalline solid. It is relatively insoluble in water but soluble in organic solvents such as ethanol and DMSO. The compound exhibits a characteristic crystalline structure.

Comment on solubility

Solubility of 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one

The solubility of 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one, with the chemical formula C15H10O6, is an intriguing topic of discussion due to its unique structural traits. This compound is characterized by multiple hydroxyl (-OH) groups, which notably influence its solubility properties.

Key points about its solubility include:

  • Polar Nature: The presence of hydroxyl groups makes the compound polar, enhancing its ability to interact with polar solvents such as water.
  • Solvent Specificity: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one is more soluble in solvents that can form hydrogen bonds, thus increasing its solubility in ethanol and methanol.
  • Temperature Dependence: Typically, solubility increases with temperature. Therefore, warming the solvent may improve the dissolution of this compound.

In summary, the solubility of 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one is significantly influenced by its functional groups, making it more soluble in polar solvents and temperature-dependent conditions. Understanding these solubility characteristics is crucial for applications in pharmaceuticals and other fields where this compound may be utilized.

Interesting facts

Interesting Facts about 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)chroman-4-one

This remarkable compound, known as 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one, belongs to the class of flavonoids and exhibits a wide range of biological activities. Here are some fascinating insights:

  • Natural Antioxidant: Known for its potent antioxidant properties, flavonoids, including this compound, help in scavenging free radicals in the body, playing a significant role in protecting cells from oxidative stress.
  • Anti-inflammatory Effects: Research has suggested that this compound may modulate inflammatory responses, indicating its potential therapeutic use in conditions associated with chronic inflammation.
  • Cardioprotective Potential: Studies have indicated that flavonoids can improve cardiovascular health by promoting vascular health and reducing blood pressure, making this compound an interesting candidate for heart health research.
  • Role in Traditional Medicine: Flavonoids like this compound have been used in various traditional medicine systems for centuries to treat a range of ailments, showcasing their longstanding value in natural remedies.
  • Source of Study: This compound is considered a model for studying the biosynthesis pathways of flavonoids, providing key insights into how these essential plant compounds are produced.

In summary, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one is more than just a simple flavonoid. Its biological activities and potential health benefits make it a captivating subject of study in the fields of pharmacology and nutritional science. As research continues, we may uncover even more about the importance of this compound in human health.

Synonyms
724434-08-6
(+/-)-Dihydrokaempferol
3,5,7-trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
3,5,7,4''-TETRAHYDROXYFLAVANONE
104486-98-8
4H-1-Benzopyran-4-one,2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, trans-
5150-32-3
KAEMPFEROL_met008
SCHEMBL39319
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chroman-4-one
CHEMBL398847
DTXSID50274279
PADQINQHPQKXNL-UHFFFAOYSA-N
BCP20472
NSC327432
4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-
AKOS032948350
AT25341
NSC-327432
NCGC00488813-01
NS00134207
2,3-Dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;
3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one #
4H-1-Benzopyran-4-one,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-