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Nefopam hydrochloride

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Identification
Molecular formula
C21H30ClN2O
CAS number
23327-57-3
IUPAC name
3,5,7-trimethyl-1-(3-piperidin-1-ium-1-ylpropyl)-3H-azepin-2-one;chloride
State
State

Nefopam hydrochloride is generally provided as a solid powder at room temperature.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
312.70
Boiling point (Kelvin)
585.85
General information
Molecular weight
309.86g/mol
Molar mass
309.8640g/mol
Density
1.1700g/cm3
Appearence

Nefopam hydrochloride typically appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of 3,5,7-trimethyl-1-(3-piperidin-1-ium-1-ylpropyl)-3H-azepin-2-one;chloride

The solubility of the compound 3,5,7-trimethyl-1-(3-piperidin-1-ium-1-ylpropyl)-3H-azepin-2-one;chloride is primarily influenced by the presence of both hydrophilic and hydrophobic characteristics. Here are some key points regarding its solubility:

  • Ionic Nature: The chloride component of the compound indicates that it possesses ionic characteristics, which often enhances solubility in polar solvents.
  • Hydrogen Bonding: The presence of the piperidine ring can contribute to hydrogen bonding, making it more soluble in water.
  • Organic Solvents: The trimethyl groups may impart hydrophobic properties, suggesting that the compound could also be soluble in organic solvents, such as ethanol or methanol.
  • Temperature Dependence: Solubility may increase with temperature, which is a common characteristic for many organic compounds.

As with any compound, it is essential to conduct empirical tests for accurate solubility assessments. In summary, 3,5,7-trimethyl-1-(3-piperidin-1-ium-1-ylpropyl)-3H-azepin-2-one;chloride likely exhibits variable solubility characteristics depending on the solvent and conditions, illustrating the complex nature of chemical solubility.

Interesting facts

Interesting Facts about 3,5,7-Trimethyl-1-(3-piperidin-1-ium-1-ylpropyl)-3H-azepin-2-one; Chloride

This intriguing compound, known for its complex structure, belongs to the class of azepines, which are seven-membered heterocycles featuring nitrogen atoms. Its unique formulation allows it to play a crucial role in various fields, including medicinal chemistry and organic synthesis. Here are some captivating aspects of this compound:

  • Dual Activity: The presence of the piperidine moiety not only enhances the solubility of the compound but also contributes to its ability to interact effectively with biological systems.
  • Versatile Synthesis: Synthesizing this compound may involve a combination of multistep reactions, making it an interesting subject for organic chemists interested in synthetic methodologies.
  • Biological Significance: Compounds of this nature often exhibit significant pharmacological activities, including potential use as analgesics, sedatives, or antipsychotics.
  • Chloride Anion Role: The chloride anion in this compound can facilitate its ionization in solution, impacting its reactivity and interaction with other molecules.

As a chemistry student or a researcher delving into this compound's properties, it's essential to note the structural complexity that results from the presence of multiple functional groups. This complexity not only contributes to the compound's unique characteristics but also raises interesting questions about its mechanism of action in biological systems. Exploring such compounds can pave the way for the development of new therapeutic agents that could significantly impact modern medicine.

Synonyms
2H-Azepin-2-one, 1,3-dihydro-1-(3-piperidinopropyl)-3,5,7-trimethyl-, hydrochloride
1-(3-Piperidinopropyl)-1,3-dihydro-3,5,7-trimethyl-2H-azepin-2-one hydrochloride
1676-46-6