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3,6-Dibenzylpiperazine-2,5-dione

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Identification
Molecular formula
C18H20N2O2
CAS number
13939-09-6
IUPAC name
3,6-dibenzylpiperazine-2,5-dione
State
State

At room temperature, 3,6-Dibenzylpiperazine-2,5-dione is typically found in a solid state due to its high melting point.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.20
Boiling point (Celsius)
327.10
Boiling point (Kelvin)
600.30
General information
Molecular weight
280.34g/mol
Molar mass
280.3420g/mol
Density
1.2540g/cm3
Appearence

3,6-Dibenzylpiperazine-2,5-dione appears as a white to off-white crystalline solid. It exhibits a clean crystalline structure, typical of many organic cyclic compounds.

Comment on solubility

Solubility of 3,6-Dibenzylpiperazine-2,5-dione

The solubility of 3,6-dibenzylpiperazine-2,5-dione can be described as moderate, influenced by its unique chemical structure. When considering solubility, several factors come into play:

  • Polarity: The presence of polar carbonyl groups (C=O) affects the overall polarity of the compound, which can enhance its solubility in polar solvents.
  • Hydrophobic Regions: The dibenzyl substituents contribute to hydrophobic characteristics, which may lead to decreased solubility in water.
  • Solvent Compatibility: This compound shows better solubility in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, and acetone.
  • Temperature Influence: As with many compounds, increasing the temperature typically increases solubility, so one can expect a better dissolution of 3,6-dibenzylpiperazine-2,5-dione at elevated temperatures.

In summary, when assessing the solubility of this compound, it's crucial to consider both the polar and non-polar aspects derived from its configuration. Therefore, a careful selection of solvent based on its properties and an understanding of temperature's role will enhance the solubility outcomes.

Interesting facts

Interesting Facts about 3,6-Dibenzylpiperazine-2,5-dione

3,6-Dibenzylpiperazine-2,5-dione is a fascinating compound that falls within the category of piperazine derivatives. These types of compounds are of significant interest in medicinal chemistry due to their diverse biological activities. Here are some compelling aspects of this compound:

  • Unique Structure: The structure of 3,6-dibenzylpiperazine-2,5-dione includes a piperazine ring which is modified by the presence of two benzyl groups and a diketone functional group. This specific arrangement contributes to its potential reactivity and interaction with biological molecules.
  • Pharmacological Properties: Compounds with piperazine moieties often display a variety of pharmacological actions, such as antidepressant, anxiolytic, and antipsychotic effects. Research in these areas is ongoing, and 3,6-dibenzylpiperazine-2,5-dione could offer insights into developing novel therapeutic agents.
  • Research Applications: This compound has drawn the attention of researchers exploring its potential in poisons and biochemical pathways, which leads to further investigations into its effectiveness as a lead compound for drug synthesis.
  • Environmental Considerations: Like many organic compounds, understanding the behavior of 3,6-dibenzylpiperazine-2,5-dione in various environments can provide useful information regarding its environmental impact and degradation pathways.

In summary, 3,6-dibenzylpiperazine-2,5-dione showcases the intricate balance between structure and function in organic compounds. Scientists continue to explore its potential, noting how structural modifications can lead to significant variations in biological activity.

Synonyms
2308-61-4
3,6-dibenzylpiperazine-2,5-dione
2,5-Piperazinedione, 3,6-bis(phenylmethyl)-
3,6-Dibenzyl-2,5-piperazinedione
Dibenzyl-3,6-dione-2,5-piperazine
2,5-PIPERAZINEDIONE, 3,6-DIBENZYL-
3,6-Dibenzylhexahydropyrazine-2,5-dione
NSC 2071
DIBENZYL-3, 6-DIOXO-2, 5-PIPERAZIN
Phenylalanine anhydride
3,6-dibenzyltetrahydro-2,5-pyrazinedione
Dibenzyl-3,5-piperazine
Oprea1_804382
2, 3,6-bis(phenylmethyl)-
SCHEMBL1226583
DIBENZYL-3, 5-PIPERAZIN
DTXSID90945759
NSC2071
JUAPMRSLDANLAS-UHFFFAOYSA-N
3,6-dibenzyl-2,5-dioxopiperazine
NSC-2071
MFCD00407233
STK366777
AKOS005092681
CCG-357036
Dibenzyl-3, 6-dioxo-2, 5-piperazine
3,6-Dibenzyl-3,6-dihydropyrazine-2,5-diol
4N-716