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Fisetin tetramethyl ether

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Identification
Molecular formula
C20H18O8
CAS number
25727-31-3
IUPAC name
3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one
State
State

At room temperature, the compound is a solid. It is often handled as a fine powder or crystalline solid in laboratory settings.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
565.10
Boiling point (Kelvin)
838.25
General information
Molecular weight
358.35g/mol
Molar mass
358.3470g/mol
Density
1.3781g/cm3
Appearence

The compound is typically found as a crystalline solid characterized by its pale yellow color. It may appear as either powder or crystalline fragments depending on the method of synthesis and preparation.

Comment on solubility

Solubility of 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one

The solubility of 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one is influenced by various factors, making it a topic of interest in chemical research. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple methoxy groups in this compound suggests a degree of polarity, which may enhance its solubility in polar solvents like methanol or ethanol.
  • Nonpolar Solvents: Conversely, the overall aromatic structure may lead to limited solubility in nonpolar solvents, such as hexane. This dual behavior means that careful consideration of solvent choice is essential.
  • Concentration Effects: At higher concentrations, solubility may decrease due to potential aggregation or crystallization of the compound.
  • pH Influence: The solution pH can also impact solubility; changes in pH may ionize functional groups, thus altering solubility dynamics.

In summary, the solubility of 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one hinges on its structural characteristics and the environmental conditions, making it a compound that warrants thorough investigation in various solvent systems.

Interesting facts

Interesting Facts about 3,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)chromen-4-one

This fascinating compound belongs to the class of flavonoids, which are widely studied for their numerous biological activities. Its intricate structure and multiple methoxy groups suggest a significant potential for pharmacological applications.

Key Features

  • Antioxidant Properties: Like many flavonoids, it possesses strong antioxidant activity, which helps in scavenging free radicals and reducing oxidative stress in cells.
  • Anti-inflammatory Effects: This compound may also exhibit anti-inflammatory properties, making it a subject of interest in research related to chronic inflammatory diseases.
  • Neuroprotective Effects: Preliminary studies suggest that it could offer protective effects on neuronal cells, indicating potential applications in neurodegenerative conditions.

The presence of multiple methoxy groups enhances the compound's stability and solubility, contributing to its effectiveness in biological systems. Recent studies indicate that flavonoids can modulate various signaling pathways, and this compound could potentially participate in such key biochemical interactions. As the field of natural product chemistry continues to evolve, compounds like 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one will undoubtedly play a crucial role in the development of new therapeutic agents.

Research Implications

Researchers are increasingly focusing on:

  • Isolating and characterizing this compound from natural sources.
  • Conducting in vitro and in vivo studies to evaluate its pharmacokinetics.
  • Assessing its synergistic effects when combined with other phytochemicals.

In conclusion, 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one is more than just a compound; it represents a promising avenue for future research that could lead to groundbreaking discoveries in the fields of medicine and health sciences.

Synonyms
Auranetin
522-16-7
Aurantin
3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chromen-4-one
6532ZBU2J5
UNII-6532ZBU2J5
FLAVONE, 3,4',6,7,8-PENTAMETHOXY-
DTXSID40966575
4H-1-Benzopyran-4-one, 3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-
3,4',6,7,8-Pentamethoxyflavone
3,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
12619-61-3
DTXCID601394208
610-798-8
CHEBI:175776
3,6,7,8,4'-pentamethoxyflavone
AAA52216
LMPK12111612
DB-228470