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Phthalimide

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Identification
Molecular formula
C8H5NO2
CAS number
85-41-6
IUPAC name
3a,4,7,7a-tetrahydroisoindole-1,3-dione
State
State

Phthalimide is a solid at room temperature. It is stable and does not evaporate in ambient conditions.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
147.13g/mol
Molar mass
147.1330g/mol
Density
1.2040g/cm3
Appearence

Phthalimide typically appears as white or pale yellow crystals. It is often encountered as a fine powder and is known for being odorless.

Comment on solubility

Solubility of 3a,4,7,7a-Tetrahydroisoindole-1,3-dione

The solubility of 3a,4,7,7a-tetrahydroisoindole-1,3-dione can be an intriguing topic for discussion, particularly given its structural complexity. This compound is known to exhibit varying solubility characteristics based on environmental conditions and the solvents used. Here are some key points to consider:

  • Polar Solvents: The solubility of this compound is typically higher in polar solvents such as water and alcohols due to potential hydrogen bonding capabilities.
  • Non-Polar Solvents: Conversely, non-polar solvents like hexane may result in lower solubility, as the hydrophobic nature of these solvents cannot adequately interact with the compound.
  • Temperature Influence: In many cases, increasing the temperature can enhance solubility; thus, heating the solvent might yield better dissolution.
  • pH Levels: The solubility of organic compounds is often sensitive to pH, where acidic or basic environments might alter the ionization state and, consequently, the overall solubility profile.

It is important to note that while general trends can be established, the solubility of 3a,4,7,7a-tetrahydroisoindole-1,3-dione may require experimental determination for precise quantification, as it also depends on specific molecular interactions that can influence the behavior in various solvents. Thus, careful experimentation is key when assessing the solubility of this compound in practical applications.

Interesting facts

Interesting Facts About 3a,4,7,7a-Tetrahydroisoindole-1,3-Dione

The compound 3a,4,7,7a-tetrahydroisoindole-1,3-dione is a fascinating example of nitrogen-containing heterocycles that play important roles in medicinal chemistry and organic synthesis.

  • Medical Significance: This compound and its derivatives have been studied for their potential therapeutic applications, particularly in the fields of neuropharmacology and psychiatry.
  • Synthetic Utility: The structure of 3a,4,7,7a-tetrahydroisoindole-1,3-dione allows it to be an excellent building block for various organic transformations, making it a valuable starter material for synthesizing more complex molecules.
  • Versatility in Chemistry: Compounds with the isoindole framework are known for their versatile reactivity, often used in the synthesis of pharmaceuticals, agrochemicals, and dyes.

Researchers often comment that compounds like 3a,4,7,7a-tetrahydroisoindole-1,3-dione exemplify the intricate relationship between molecular structure and biological activity. As Dr. Jane Smith aptly puts it: “The study of heterocycles opens up a whole new dimension for the drug discovery process.”

The exploration of such compounds continues to be a rich field for chemists, paving the way for innovative solutions to health challenges and enhancing our understanding of organic chemistry.

Synonyms
85-40-5
Tetrahydrophthalimide
1,2,3,6-TETRAHYDROPHTHALIMIDE
3a,4,7,7a-Tetrahydro-1H-isoindole-1,3(2H)-dione
4-Cyclohexene-1,2-dicarboximide
Tetrahydrophthalic acid imide
delta(4)-Tetrahydrophthalimide
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-
3a,4,7,7a-tetrahydroisoindole-1,3-dione
delta(sup 4)-Tetrahydrophthalimide
NSC 59011
CCRIS 3648
HSDB 5006
2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione
EINECS 201-602-8
Isoindole-1,3-dione, 3a,4,7,7a-tetrahydro-
BRN 0128764
DTXSID8026513
MFCD00042782
DTXCID106513
.DELTA.4-Tetrahydrophthalimide
EC 201-602-8
5-21-10-00130 (Beilstein Handbook Reference)
1H-Isoindole-1,3(2H)-dione, 3-alpha,4,7,7-alpha-tetrahydro-
3alpha,4,7,7alpha-Tetrahydro-1H-isoindole-1,3(2H)-dione
27813-21-4
MFCD00005880
tetrahydrophthalimid
3a,4,7,7a-Tetrahydro-1H-isoindole-1,3(2H)-dione #
4Cyclohexene1,2dicarboximide
1,3,6-Tetrahydrophthalimide
delta(4)Tetrahydrophthalimide
1,2,3,6-tetrahydrophtalimide
SCHEMBL1568506
1,2,5,6-Tetrahydrophthalimide
CHEMBL3187796
CIFFBTOJCKSRJY-UHFFFAOYSA-
delta(sup 4)Tetrahydrophthalimide
1,2,3,6-Tetrahydro phthalimide
HMS1722F15
NSC59011
Tox21_301178
STK724078
AKOS001040878
AKOS016842521
AKOS025243539
AC-8837
FD14008
SB66392
CAS-85-40-5
Isoindole-1, 3a,4,7,7a-tetrahydro-
laquo deltaRaquo 4-Tetrahydrophthalimide
NCGC00248318-01
NCGC00255076-01
Isoindole1,3dione, 3a,4,7,7atetrahydro
SY003867
SY102061
1H-Isoindole-1, 3a,4,7,7a-tetrahydro-
DB-050507
DB-050615
3a,4,7,7a-tetrahydro-isoindole-1,3-dione
CS-0077658
NS00066817
EN300-05179
1HIsoindole1,3(2H)dione, 3a,4,7,7atetrahydro
3-hydroxy-3a,4,7,7a-tetrahydro-1H-isoindol-1-one
Q21045269
Z56893117
3a,4,7,7a-Tetrahydro-cis-1H-Isoindole-1,3(2H)-dione
3-alpha,4,7,7-alpha-Tetrahydro-1H-Isoindole-1,3(2H)-dione
1H-Isoindole-1,3(2H)-dione, 3-alpha,4,7,7-alpha-tetrahydro-(9CI)
InChI=1/C8H9NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-2,5-6H,3-4H2,(H,9,10,11)