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Identification
Molecular formula
C17H14N4O2
CAS number
18948-11-5
IUPAC name
3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
310.33g/mol
Molar mass
310.3330g/mol
Density
1.3820g/cm3
Appearence

This compound typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione

The solubility of 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione is an intriguing aspect that merits attention for researchers and chemists alike. This compound, being part of a complex fused heterocyclic system, showcases some unique solubility characteristics. Here are a few key points to consider:

  • Polar vs. Nonpolar Solvents: Generally, the solubility of compounds like 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione may be higher in polar solvents due to the presence of nitrogen atoms that can engage in hydrogen bonding.
  • Influence of Structure: The presence of multiple phenyl groups in the structure can contribute to hydrophobic interactions, potentially hindering solubility in polar solvents while enhancing solubility in nonpolar solvents.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature, making it beneficial to explore varying conditions when attempting to dissolve this compound.
  • pH Dependence: The solubility of this compound might be affected by pH levels, particularly if acidic or basic conditions can affect the ionization of functional groups.

In conclusion, the solubility of 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione is a multifaceted topic that can greatly influence its application in various fields, including pharmaceuticals and materials science. Understanding these solubility characteristics is crucial for optimizing experiments and applications.

Interesting facts

Interesting Facts about 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione

This fascinating compound, known as a derivative of imidazole, has garnered significant attention in the field of medicinal chemistry and organic synthesis. Here are some interesting highlights:

  • Biological Activity: This compound has been studied for its potential pharmacological properties, particularly as an inhibitor against various biological targets. Its structure allows for interactions that could lead to therapeutic benefits.
  • Synthetic Versatility: The multi-functional nature of imidazo compounds makes them valuable in synthetic organic chemistry. They can serve as intermediates or building blocks for more complex molecular architectures.
  • Research Applications: Researchers are exploring variations of this compound to enhance bioactivity or reduce toxicity, showcasing its importance in drug development.
  • Structural Interest: The presence of diphenyl groups adds unique steric and electronic properties to the compound, making it an intriguing subject for the study of structure-activity relationships.
  • Historical Significance: Imidazole and its derivatives have been known since the early 20th century, yet modern advancements in chemistry have given rise to new applications and discoveries related to these compounds.

As put forth by many chemists, "The magic of chemistry lies not just in the reaction but in the potential discoveries that lie within each molecule." This statement rings especially true for compounds like 3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione, where the complexity of its structure hints at untapped possibilities in science and medicine.


Through continued research and experimentation, the unique properties of this compound may lead to breakthroughs that enhance our understanding of chemical interactions and the development of novel therapeutic agents.

Synonyms
5157-15-3
Diphenylglycoluril
GLYCOLURIL, 3a,6a-DIPHENYL-
3a,6a-Diphenyloctahydroimidazo[4,5-d]imidazole-2,5-dione
7,8-Diphenylglycoluril
Diphenylglycoluril, cis-
3a,6a-Diphenyltetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione
3a,6a-Diphenylglycoluril
NSC 87602
3a,6a-diphenyl-1,3,4,6-tetrahydroimidazo[4,5-d]imidazole-2,5-dione
NSC-87602
NSC 144422
NSC-144422
MLS002694765
Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-3a,6a-diphenyl-
NSC144422
C15I92344M
101241-21-8
Glycoluril,8-diphenyl-
Glycoluril,6a-diphenyl-
3a,6a-Diphenyltetrahydroimidazo(4,5-d)imidazole-2,5(1H,3H)-dione
Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-3a,6a-diphenyl-, cis-
3a,6a-Diphenyltetra-hydroimidazo[4,5-d]imidazole-2,5(1H, 3H)-dione
WLN: T55 BMVM FMVMTJ AR& ER
Glycoluril, 7,8-diphenyl-
3a,6a-Diphenylglycouril
Imidazo[4,5(1H,3H)-dione, tetrahydro-3a,6a-diphenyl-
BRN 0296281
UNII-C15I92344M
Phenytoin specified impurity D [EP]
cis-diphenylglycoluril
starbld0017950
3a,6a-Diphenyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dione
Phenytoin sodium specified impurity D [EP]
Oprea1_009459
Oprea1_159229
SCHEMBL3973309
3Alpha,6alpha-diphenylglycoluril
CHEMBL1904613
3a,6a-diphenylperhydroimidazo[4,5-d]imidazole-2,5-dione
DTXSID80199522
WUDVGTHXCLJVJN-UHFFFAOYSA-N
HMS1755D12
HMS3083L12
NSC87602
CCG-52404
STL301828
STL417963
AKOS000416585
AKOS016401580
FD22497
AS-82877
SMR000060564
PHENYTOIN IMPURITY D [EP IMPURITY]
NS00097922
G77469
PHENYTOIN SODIUM IMPURITY D [EP IMPURITY]
SR-01000641643-1
BRD-K13644454-001-05-5
Q27275041
Z56791218
3a,6a-diphenyl-1,3a,4,6a-tetrahydroimidazo[4,5-d]imidazole-2,5-diol
Tetrahydro-3a,6a-diphenyl-imidazo[4,5-d]imidazole-2,5(1H,3H)-dione;3a,6a-Diphenylglycoluril;NSC 144422