Interesting facts
Interesting Facts about 9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
This fascinating compound is a member of the azulene family, renowned for its rich blue color. Azulenes have a unique structure that stands out in the world of organic chemistry, offering exciting opportunities for scientific exploration. Here are some interesting aspects of this compound:
- Biological Significance: Compounds in the azulene family, including this one, are noted for their potential therapeutic properties. They may exhibit anti-inflammatory and antioxidant activities, making them targets for pharmaceutical research.
- Synthetic Challenges: The synthesis of such complex structures often requires intricate multi-step processes, highlighting the challenges and creativity involved in modern organic chemistry. Scientists develop various reactions and methodologies to construct these compounds efficiently.
- Applications in Dyes: Due to their vivid colors, azulenes are sometimes employed in dye applications. This compound's potential as a dye provides a fascinating intersection between chemistry and art, showcasing the practical applications of organic structures.
- Unique Structural Features: The presence of both hydroxy and methyl groups alongside a methylene bridge lends this compound distinctive properties, impacting its reactivity and interactions with other molecules. The specific stereochemistry, denoted by the detailed nomenclature, plays a crucial role in determining how this compound behaves in various chemical environments.
- Research Potential: Scientists continue to investigate derivatives of azulenes for their unique photophysical properties, opening doors to advancements in materials science and nanotechnology.
In summary, the compound exemplifies the intricate beauty and complexity of organic molecules, serving as a reminder of the endless potential within the realm of chemistry. As we continue to study compounds like this, we unravel the secrets of nature and potentially pave the way for innovative applications that can benefit various fields.
Synonyms
HELENALIN
6754-13-8
Helenalin A
PF 56
HSDB 3490
NSC 85236
UNII-4GUY9L896T
BRN 0028081
4GUY9L896T
CHEBI:5635
(3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
HELENALIN [MI]
HELENALIN [HSDB]
NSC-85236
(-)-HELENALIN
6alpha,8beta-Dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oic acid 12,8-lactone
Ambrosa-2,11(13)-dien-12-oic acid, 6-alpha,8-beta-dihydroxy-4-oxo-, 12,8-lactone
DTXSID50217868
4-18-00-01434 (Beilstein Handbook Reference)
Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone
(3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
(3aS)-3,3aalpha,4alpha,4a,7aalpha,8,9,9aalpha-Octahydro-4-hydroxy-4abeta,8 alpha-dimethyl-3-methyleneazuleno(6,5-b)-furan-2,5-dione
Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-
6.ALPHA.,8.BETA.-DIHYDROXY-4-OXOAMBROSA-2,11(13)-DIEN-12-OIC ACID 12,8-LACTONE
(3aS)-3,3aalpha,4alpha,4a,7aalpha,8,9,9aalpha-octahydro-4-hydroxy-4abeta,8alpha-dimethyl-3-methyleneazuleno(6,5-b)-furan-2,5-dione
(3aS,4S,4aR,7aR,8R,9aR)-4-hydroxy-4a,8-dimethyl-3-methylidene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione
(3AS-(3A.ALPHA.,4.ALPHA.,4A.BETA.,7A.ALPHA.,8.ALPHA.,9A.ALPHA.))-3,3A,4,4A,7A,8,9,9A-OCTAHYDRO-4-HYDROXY-4A,8-DIMETHYL-3-METHYLENEAZULENO(6,5-B)FURAN-2,5-DIONE
(3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno(6,7-b)furan-2,8-dione
(3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno(6,7-b)furan-2,8-dione
(3aS,4S,4aR,7aR,8R,9aR)-4-hydroxy-4a,8-dimethyl-3-methylidene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno(6,5-b)furan-2,5-dione
DTXCID00140359
6alpha,8betaDihydroxy4oxoambrosa2,11(13)dien12oic acid 12,8lactone
Ambrosa2,11(13)dien12oic acid, 6alpha,8betadihydroxy4oxo, 12,8lactone
Ambrosa-2,11(13)-dien-12-oic acid, 6alpha,8beta-dihydroxy-4-oxo-, 12,8-lactone (8CI)
(3aS)3,3aalpha,4alpha,4a,7aalpha,8,9,9aalphaOctahydro4hydroxy4abeta,8 alphadimethyl3methyleneazuleno(6,5b)furan2,5dione
(3AS-(3AALPHA,4ALPHA,4ABETA,7AALPHA,8ALPHA,9AALPHA))-3,3A,4,4A,7A,8,9,9A-OCTAHYDRO-4-HYDROXY-4A,8-DIMETHYL-3-METHYLENEAZULENO(6,5-B)FURAN-2,5-DIONE
Azuleno(6,5-b)furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, (3aS-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-(9CI)
Azuleno(6,5b)furan2,5dione, 3,3a,4,4a,7a,8,9,9aoctahydro4hydroxy4a,8dimethyl3methylene, (3aS(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))
NSC85236
MLS000728512
SMR000445626
(3aR,5R,5aR,8aR,9S,9aS)-9-Hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[7,6-d]furan-2,8-dione
MLS002701927
NF-kappaB inhibitor
BSPBio_001312
cid_23205
SCHEMBL161593
CHEMBL338474
BDBM43484
HMS1791B14
HMS1989B14
HMS2236C04
EX-A10269
HB3927
AKOS040741831
Ambrosa-2,11(13)-dien-12-oic acid, 6.alpha.,8.beta.-dihydroxy-4-oxo-, 12,8-lactone
NCGC00163416-01
NCGC00163416-02
Azuleno[6,5-b]furan-2,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, [3aS-(3a.alpha.,4.alpha.,4a.beta.,7a.alpha.,8.alpha.,9a.alpha.)]-
MS-23694
NCI60_041870
HY-119970
CS-0078850
NS00094722
C09473
G13013
Q387505
WLN: T C575 DYVO MV KUTJ A1 BQ DU1 I1
BRD-K26302255-001-02-3
Ambrosa-2, 6.alpha.,8.beta.-dihydroxy-4-oxo-, 12,8-lactone
(3aR,5R,5aR,8aR,9S,9aS)-5,8a-dimethyl-1-methylidene-9-oxidanyl-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
(3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-quinone
4-Hydroxy-4a,8-dimethyl-3-methylene-3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione
Azuleno[6,5-dione, 3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, [3aS-(3a.alpha.,4.alpha.,4a.beta.,7a.alpha.,8.alpha.,9a.alpha.)]-
Solubility of (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione
The solubility of this compound in various solvents can be quite intriguing due to its complex structure. Understanding its solubility helps in numerous applications ranging from synthesis to medicinal chemistry. Here are some key points to consider:
It is often stated that, "solubility is a key property that influences the bioavailability and distribution of chemicals in biological systems." Thus, careful evaluation of solubility is essential for practical applications of this intriguing compound.