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Aphanorphine

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Identification
Molecular formula
C15H18O4
CAS number
28752-07-0
IUPAC name
(3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione
State
State

Aphanorphine is typically a solid at room temperature.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
262.30g/mol
Molar mass
262.2910g/mol
Density
1.2300g/cm3
Appearence

Aphanorphine is a white crystalline solid.

Comment on solubility

Solubility of (3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione

The solubility of the compound (3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione is a complex subject, primarily because of its unique structural features. Understanding the factors that influence its solubility can provide insights into its behavior in various environments.

Factors Influencing Solubility

Several key factors affect the solubility of this compound:

  • Polarity: Due to the presence of hydroxyl groups, the polarity of the molecule increases, potentially enhancing solubility in polar solvents.
  • Hydrogen Bonding: The hydroxyl functional group may engage in hydrogen bonding with solvents, aiding in solvation.
  • Molecular Size: The relatively large structure may hinder solubility in certain solvents due to steric hindrance.
  • pH Sensitivity: As a dione, this compound may exhibit different solubility characteristics depending on the pH of the surrounding environment.

Solubility Characteristics

In terms of actual solubility, it is noted that:

  • The compound is likely soluble in alcohols and ketones due to their polar nature.
  • It may have limited solubility in non-polar solvents like hexane or benzene owing to its higher polarity.
  • Ionic interactions and potential solvation effects can alter its solubility in aqueous solutions.

In summary, the solubility of this compound is contingent upon multiple factors, including its polarity, ability to form hydrogen bonds, molecular size, and the pH levels of the solvent environment. Understanding these attributes is essential for predicting and optimizing its use in various applications.

Interesting facts

Discovering the Wonders of (3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione

(3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione is a sophisticated compound that merges both structural complexity and potential applications in various fields. Below are some intriguing aspects of this compound:

  • Chemical Structure: The intricate architecture of this compound includes multiple chiral centers, which can result in distinct isomers with varying biological properties. This complexity opens up fascinating avenues in stereochemistry.
  • Natural Origins: Compounds similar to this azuleno derivative can be found in nature. Azulenes are known for their vibrant colors and have been associated with essential oils in plants, demonstrating the compound's relevance in botanical studies.
  • Potential Applications: Though research is still in its early stages, the unique properties of compounds like this one could lead to applications in pharmaceuticals, particularly due to their possible antimicrobial or anti-inflammatory effects. Investigating such compounds may yield new therapeutic agents.
  • Unique Functional Groups: The presence of a hydroxyl group and dione structures in the compound suggests potential for engaging in hydrogen bonding, which can influence its reactivity and interaction with other substances.

As you delve deeper into this compound, consider the following quote from renowned chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." This sentiment underscores the importance of exploring compounds like (3aS,6S,6aS,9aS,9bR)-6a-hydroxy-6,9a-dimethyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-2,9-dione, as each unique structure can lead to groundbreaking discoveries.

In summary, the exploration of this compound serves as an exciting intersection of natural products chemistry and synthetic organic research, inspiring scientists to unlock new possibilities in material science and medicine.

Synonyms
Coronopolin
NSC 85242