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Alstonine

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Identification
Molecular formula
C23H26N2O3
CAS number
642-00-8
IUPAC name
(3'aS,7'aR,9S,10aS)-3-hydroxy-3',6',10,11b-tetramethyl-spiro[1,2,3,4,6,6a,6b,7,8,10,10a,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one
State
State

At room temperature, alstonine exists as a solid.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
351.47g/mol
Molar mass
351.4850g/mol
Density
1.1900g/cm3
Appearence

Alstonine typically appears as a yellowish-brown crystalline powder.

Comment on solubility

Solubility of (3'aS,7'aR,9S,10aS)-3-hydroxy-3',6',10,11b-tetramethyl-spiro[1,2,3,4,6,6a,6b,7,8,10,10a,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one

The solubility of the compound (3'aS,7'aR,9S,10aS)-3-hydroxy-3',6',10,11b-tetramethyl-spiro[1,2,3,4,6,6a,6b,7,8,10,10a,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one can be quite complex due to its intricate structure. The solubility profile of such organic compounds is influenced by several factors:

  • Polarity: The presence of functional groups, such as hydroxyl (-OH), can enhance water solubility. However, the overall hydrophobic character from the remaining structure may limit it.
  • Temperature: Increased temperatures often enhance solubility for many organic compounds, which may play a crucial role in how this compound behaves in different solvents.
  • Solvent type: Solubility varies significantly between polar and non-polar solvents. This compound may show better solubility in organic solvents compared to water.

In general, higher molecular weight compounds with extensive branching or fused rings tend to yield lower solubility in water, while small, unbranched molecules might dissolve more readily. Therefore, for this specific compound, while it may exhibit some degree of solubility in organic solvents, its overall solubility in aqueous environments is likely moderate to low, delineating the classic trade-off seen with complex organic molecules.

Ultimately, exploring the solubility in various environments will provide a more comprehensive understanding of this compound's chemical behavior and potential applications.

Interesting facts

Interesting Facts about (3'aS,7'aR,9S,10aS)-3-hydroxy-3',6',10,11b-tetramethyl-spiro[1,2,3,4,6,6a,6b,7,8,10,10a,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one

This complex and fascinating compound belongs to a unique class of molecules that exhibit intriguing structural features. As a naturally occurring derivative, it can be associated with various biological activities. Here are some captivating aspects:

  • Stereochemistry: The specific stereochemical configuration, indicated by the multiple stereocenters, plays a pivotal role in determining the compound's reactivity and biological interactions. This highlights the importance of stereochemistry in organic chemistry.
  • Structural Complexity: The compound's structure presents a spirocyclic framework, where two rings share a single atom. Such features often lead to unique properties, influencing both the compound's color and its function in biological systems.
  • Biological Relevance: Compounds of this nature are often found in nature and may exhibit pharmacological properties. They can be part of studies focused on drug design or natural product chemistry, showcasing their potential as therapeutic agents.
  • Research and Development: The synthetic pathways to create this compound can be of great interest in organic synthesis. Chemists are continually exploring how to efficiently manufacture such compounds and study their potential applications in medicinal chemistry.
  • Interdisciplinary Connections: This compound exemplifies the intersection of chemistry, biology, and pharmacology. Students and researchers can explore its implications in fields like biochemistry, therapeutic drug development, and even environmental science, shedding light on its relevance in both nature and laboratory settings.

The synthesis and study of this intriguing compound underline the complexity and beauty of organic chemistry, showcasing how such intricate molecules can have significant impacts on both science and medicine.