Skip to main content

Etonitazene

ADVERTISEMENT
Identification
Molecular formula
C23H30N4O3
CAS number
911-65-9
IUPAC name
(3R)-1-[(3S,5R,8S,9S,10R,13S,14S,17R)-17-[1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-isopropyl-azetidin-2-one
State
State

At room temperature, Etonitazene is typically found in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
433.00
Boiling point (Kelvin)
706.15
General information
Molecular weight
609.74g/mol
Molar mass
609.7430g/mol
Density
1.1500g/cm3
Appearence

Etonitazene appears as a white powder. It is typically crystalline and has no discernible odor. Its solid powder form is consistent in texture and color, providing a uniform appearance.

Comment on solubility

Solubility of (3R)-1-[(3S,5R,8S,9S,10R,13S,14S,17R)-17-[1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-isopropyl-azetidin-2-one

The compound (3R)-1-[(3S,5R,8S,9S,10R,13S,14S,17R)-17-[1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-isopropyl-azetidin-2-one exhibits interesting solubility characteristics that make it relevant in various chemical and pharmaceutical applications.

Factors Influencing Solubility

The solubility of this complex compound can be influenced by several key factors:

  • Polarity: The presence of groups such as dimethylamino may enhance the compound's polarity, potentially increasing its solubility in polar solvents.
  • Molecular Weight: With a relatively high molecular weight due to its intricate structure, solubility may be lower in conventional solvents.
  • Structural Configuration: The stereochemistry of the compound may also play a role, impacting how it interacts with solvent molecules.

Solvent Compatibility

In terms of solvent compatibility, one might expect the following:

  • Water: Likely to exhibit low solubility due to its non-polar characteristics.
  • Organic Solvents: More soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), where its structural components can better solvate.

Overall, understanding the solubility of this compound is essential for its application in drug formulation, where solubility can significantly influence bioavailability. As the saying goes, "Solubility is key!"

Interesting facts

Interesting Facts about (3R)-1-[(3S,5R,8S,9S,10R,13S,14S,17R)-17-[1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-isopropyl-azetidin-2-one

This particular compound is a fascinating example of pharmaceutical chemistry, showcasing a high degree of stereochemical complexity. Here are some interesting points about this compound:

  • Stereo-specificity: The numerous chiral centers present in the compound indicate that its biological activity can significantly depend on its 3D orientation. This is crucial for interactions with biological macromolecules such as proteins and enzymes.
  • Structural Diversity: The compound combines multiple functional groups, most notably the azetidin-2-one ring and a complex tetradecahydrocyclopenta[a]phenanthrene moiety, which contribute to its unique properties and potential applications in medicine.
  • Biological Significance: Compounds with similar structural features are often researched for their potential therapeutic uses, including anti-tumor and anti-inflammatory effects. Investigating how this compound interacts at the molecular level can lead to breakthroughs in the development of new drugs.
  • Multifunctionality: The presence of the dimethylamino group suggests promising pharmacological profiles due to its ability to modulate biochemical interactions. Compounds like this are often considered for use in the treatment of various diseases, including cancer.
  • Research Potential: Research involving this compound can provide insights into the development of next-generation pharmaceuticals. Its complex structure makes it an interesting candidate for synthetic chemists aiming to create derivatives with improved efficacy and reduced side effects.

In summary, the depth of its molecular architecture provides immense opportunities for study and application. As scientists continue to unravel the mechanisms behind such compounds, they hold the potential to shape future therapeutic strategies.

Synonyms
Pachystermine A
6156-99-6
2-Azetidinone, 1-(20-alpha-(dimethylamino)-4-oxo-5-alpha-pregnan-3-beta-yl)-3-isopropyl-, (3R)-
DTXSID00977142
NS00094283
20-(Dimethylamino)-3-[2-oxo-3-(propan-2-yl)azetidin-1-yl]pregnan-4-one