Interesting facts
Interesting Facts about (3R)-3-hydroxy-4-(trimethylammonio)butanoate
(3R)-3-hydroxy-4-(trimethylammonio)butanoate, often recognized in biochemical contexts, is an intriguing compound with several noteworthy aspects:
- Biochemical Significance: This compound plays a crucial role in various biological systems, acting as a key metabolite in amino acid biosynthesis and metabolism.
- Chirality: The designation of (3R) indicates that this compound has a specific stereochemistry, which is vital for its function in biological processes. Chirality affects how the compound interacts with enzymes and receptors in the body.
- Use in Research: (3R)-3-hydroxy-4-(trimethylammonio)butanoate has been studied for its potential therapeutic applications, highlighting its role in neurotransmission and cellular signaling.
- Quaternary Ammonium Structure: Its trimethylammonio group contributes to its properties, including solubility and binding affinities, crucial for understanding its interactions in biological systems.
- pH Sensitivity: As a zwitterionic compound, it can exist in both positive and negative charge states depending on the environmental pH, which can influence its behavior in physiological conditions.
As a testament to its versatility, researchers continue to explore its implications in fields ranging from pharmacology to neurobiology. To quote a contemporary research paper, "The role of (3R)-3-hydroxy-4-(trimethylammonio)butanoate in cellular metabolism cannot be overstated, as it bridges various metabolic pathways." Its exploration is a prime example of how a single compound can intertwine with multiple aspects of biology, chemistry, and medicine.
Synonyms
L-carnitine
Levocarnitine
541-15-1
(R)-Carnitine
Carnitor
vitamin BT
(-)-Carnitine
Karnitin
(-)-L-Carnitine
L-(-)-Carnitine
Levocarnitina
Carnitene
Metina
Carnitine, (-)-
Levocarnitinum
Carnitolo
Carnovis
Lefcar
Carnitor SF
Levocarnitinum [Latin]
gamma-Trimethyl-beta-hydroxybutyrobetaine
(3R)-3-hydroxy-4-(trimethylammonio)butanoate
vitamin B T
Carnitine, L-
gamma-Trimethyl-ammonium-beta-hydroxybutirate
L-gamma-trimethyl-beta-hydroxybutyrobetaine
R-(-)-3-hydroxy-4-trimethylaminobutyrate
3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium
44985-71-9
EINECS 208-768-0
UNII-0G389FZZ9M
NSC-759132
0G389FZZ9M
CHEBI:16347
HSDB 7588
DTXSID4023208
Levocarnitine [USAN:USP:INN:BAN]
NSC 759132
Levocarnitinum (Latin)
gamma-L-trimethyl-beta-hydroxybutyrobetaine
(2r)-3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium inner salt
LEVOCARNITINE (MART.)
LEVOCARNITINE [MART.]
LEVOCARNITINE (USP-RS)
LEVOCARNITINE [USP-RS]
LEVOCARNITINE (EP MONOGRAPH)
LEVOCARNITINE [EP MONOGRAPH]
L Carnitine
Levocarnitine (USAN:USP:INN:BAN)
LEVOCARNITINE (USP MONOGRAPH)
LEVOCARNITINE [USP MONOGRAPH]
Levocarnil
Levocarnitin
Nefrocarnit
L-Carn
LEVOCARNITINE SF
Levocarnitine Oral Solution
DTXCID903208
A16AA01
3-Hydroxy-4-(trimethylammonio) butanoate
(R)-3-Hydroxy-4-trimethylammoniobutanoate
beta-Hydroxy-gamma-N,N,N-trimethylammoniobutyrate
Levocarnitine Oral Solution (Suguar Free) 1 g/10 mL
R(-)-beta-Hydroxy-gamma-(N,N,N-trimethylammonio)butyrate
208-768-0
bicarnesine
L-Carnitine inner salt
Carniking
Carnilean
Levocarnitina [Spanish]
Carniking 50
(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
1-CARNITINE
3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt
DRG-0211
(R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide
(L-3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide, inner salt
levocarnitine HCl
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (R)-
(R)-3-hydroxy-4-(trimethylammonio)butanoate
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, (R)-
(3-Carboxy-2-hydroxypropyl)trimethyl-ammonium hydroxide, inner salt
CHEMBL1149
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
Carnicor
Carrier
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
L-carnitine Base
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (2R)-
Oristar lch
Levocarnitine [USAN:INN]
Carnitor (TN)
SMR000112475
carnitine (L-form)
gamma-Trimethyl-hydroxybutyrobetaine
Levocarnitine;Vitamin B(T)
3-hydroxy-4-trimethylammoniobutanoate
Carnipass
delta-carnitine
Levocarnitine (JAN/USP/INN)
L-Carnitin
Carnipass 20
1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-
CARNITINE HYDROCHLORIDE, DL-
(R)-3-Hydroxy-4-trimethylammoniobutyrate
L-Carnitine (Standard)
(R)-3-Hydroxy-4-(trimethylammonio)butyrate
bmse000211
L-CARNITINE [FCC]
L-Carnitin 100 microg/mL in Acetonitrile
LEVOCARNITINE [INN]
LEVOCARNITINE [JAN]
L-carnitine (Levocarnitine)
L-CARNITINE [VANDF]
LEVOCARNITINE [HSDB]
LEVOCARNITINE [USAN]
SCHEMBL21970
LEVOCARNITINE [VANDF]
MLS001332549
MLS001332550
BIDD:GT0603
(3R)-(-)-3-Hydroxy-4-(trimethylammonio)butanoate
Carnitine dl-form hydrochloride
LEVOCARNITINE [WHO-DD]
GTPL4780
HY-B0399R
MSK1534
HMS2093J13
HMS2267H24
Pharmakon1600-01505437
LEVOCARNITINE [ORANGE BOOK]
HY-B0399
(R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide, inner salt
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide,inner salt
BDBM50037268
c0049
NSC741806
NSC759132
s2388
AKOS005267245
BCP9000830
CCG-213241
DB00583
FC02224
KS-1422
NSC-741806
3-hydroxy-4-trimethylammoniobutanoic acid
AS-11974
L-Carnitine inner salt, synthetic, >=98%
NS00076300
C00318
D02176
AB00919083_05
AB00919083_06
EN300-6495783
Q20735709
Vitamin BT;(-)-b-Hydroxy-y-(trimethylammonio)butyrate
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin BT
Levocarnitine, European Pharmacopoeia (EP) Reference Standard
Levocarnitine, United States Pharmacopeia (USP) Reference Standard
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (2R)- (9CI)
Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L- (8CI)
Levocarnitine, Pharmaceutical Secondary Standard; Certified Reference Material
Solubility of (3R)-3-hydroxy-4-(trimethylammonio)butanoate
The solubility of (3R)-3-hydroxy-4-(trimethylammonio)butanoate, a quaternary ammonium compound, is quite intriguing due to its structural characteristics. The presence of a charged trimethylammonio group greatly influences its solubility profile. Here are some key points to consider:
As quoted from a well-known chemistry text, “the solubility of ionic compounds is often significantly affected by the nature of the solvent.” This emphasizes the critical role that the solvent type plays in the solubility behavior of salts and charged species.
In summary, the solubility of (3R)-3-hydroxy-4-(trimethylammonio)butanoate highlights the importance of molecular structure in determining how well a compound can dissolve in various media, illustrating the fascinating interplay between ionic interactions and solvent properties.