Skip to main content

Corticosterone 21-acetate

ADVERTISEMENT
Identification
Molecular formula
C24H34O6
CAS number
62-87-7
IUPAC name
(3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one;[2-[(3R,5S,8S,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
State
State

At room temperature, Corticosterone 21-acetate is solid. It is stable under standard conditions and typically requires specific storage considerations such as low humidity and stable temperature due to its crystalline nature.

Melting point (Celsius)
302.00
Melting point (Kelvin)
575.15
Boiling point (Celsius)
554.10
Boiling point (Kelvin)
827.20
General information
Molecular weight
434.53g/mol
Molar mass
434.5830g/mol
Density
1.1300g/cm3
Appearence

Corticosterone 21-acetate typically appears as a white crystalline powder. Its exact appearance can be affected by its purity and environmental conditions such as humidity.

Comment on solubility

Solubility Characteristics

The solubility of the compound named (3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one can be described as follows:

  • Polarity: The presence of hydroxyl groups and acetyl moieties suggests that the compound has some polar characteristics, which may increase its solubility in polar solvents.
  • Solvent Compatibility: Expect moderate solubility in solvents such as ethanol, methanol, and possibly water; however, its solubility might be significantly lower in non-polar solvents due to its larger hydrophobic hydrocarbon structure.
  • Effect of Functional Groups: Functional groups that can form hydrogen bonds will enhance solubility in certain solvents, whereas the bulky hydrocarbon framework can hinder it.
  • Concentration Dependency: The solubility may vary with concentration, showing differences at different temperatures and pH levels.

In summary, while the compound is anticipated to exhibit some solubility in polar solvents due to its functional groups, its overall solubility profile would likely reflect the balance between its polar and non-polar characteristics. Future studies could provide more detailed insights into its solubility dynamics under varying conditions.

Interesting facts

Interesting Facts About the Compound

This fascinating compound is known for its complex structure and significant biological activity. Here are some intriguing points to consider:

  • Stereochemistry: The compound features a specific stereochemistry with multiple chiral centers, making it a stereoisomer. This aspect contributes to its unique properties and interactions with biological systems.
  • Natural Occurrence: Compounds similar to this one can often be found in natural sources such as plants or fungi, suggesting potential medicinal properties worth exploring.
  • Biological Activity: Due to its structural characteristics, this compound may exhibit interesting activities such as anti-inflammatory or anticancer properties. Research in this area is ongoing and could lead to the development of new therapeutic agents.
  • Synthesis Variants: The synthetic pathways for creating this compound can vary greatly, indicating diverse methodologies in organic chemistry. Chemists often explore alternative routes to optimize yield and purity.
  • Analytical Techniques: Its analysis typically involves advanced techniques such as NMR (Nuclear Magnetic Resonance) and mass spectrometry, revealing its intricate structure and potential transformations under various conditions.

As researchers delve deeper into the characteristics and applications of this compound, it serves as a reminder of the complexity and beauty found within organic chemistry. The marriage of intricate molecular structure and profound biological implications highlights the significance of studying such compounds in the quest for new medical therapies.

Synonyms
8067-82-1
Pregnane-11,20-dione, 21-(acetyloxy)-3-hydroxy-, (3alpha,5alpha)-, mixt. with (3alpha,5alpha)-3-hydroxypregnane-11,20-dione
Alfathesin
ALTHESIN
Alphadione
Saffan
(3R,5S,8S,9S,10S,13S,14S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one;[2-[(3R,5S,8S,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Alfatesine
Aurantex
Alfatesine [French]
CT-1341
alfaxolone/alfadolone
DTXSID001001405
Q4721889
3-Hydroxy-11,20-dioxopregnan-21-yl acetate--3-hydroxypregnane-11,20-dione (1/1)