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SGBR-128

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Identification
Molecular formula
C25H31ClN2O2
CAS number
1498409-28-5
IUPAC name
(3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione;chloride
State
State

At room temperature, SGBR-128 exists as a solid. It is stable under standard atmospheric conditions and often used in its powdered form for various applications.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
474.02g/mol
Molar mass
474.0240g/mol
Density
1.1500g/cm3
Appearence

SGBR-128 often appears as a white to off-white crystalline powder. This compound is typically odorless and has a fine particulate nature.

Comment on solubility

Solubility of (3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione; chloride

The solubility of the compound (3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione; chloride can be influenced by several key factors:

  • Polarity: This compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, which can lead to varying degrees of solubility in different solvents.
  • Ionization: As a chloride salt, the presence of the chloride ion can enhance its solubility in polar solvents, particularly water.
  • Temperature: Increased temperature often improves solubility, as it allows for greater molecular movement and interaction.
  • pH Levels: The solubility may vary with changes in pH, especially if the compound can ionize in different pH conditions.

In many cases, compounds resembling (3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione exhibit good solubility in solvents such as:
- Water
- Alcohols (e.g., ethanol, methanol)
- Acetone

However, factors like molecular weight and crystal structure could also play significant roles. It is important to note, as a general observation, that complex organic compounds often exhibit limited solubility in non-polar solvents due to their extensive polar functionalities.

Understanding these solubility characteristics is crucial for applications in pharmaceuticals, as solubility directly influences bioavailability and overall efficacy.

Interesting facts

Interesting Facts about (3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione;chloride

This fascinating compound belongs to a class of chemical substances known as piperidine derivatives, which are highly praised in the field of medicinal chemistry due to their diverse biological activities. Here are some intriguing points worth noting about this compound:

  • Pharmaceutical Relevance: Piperidine-based compounds have been extensively studied for their potential as therapeutic agents. They often exhibit properties such as analgesic, anti-inflammatory, and antidepressant effects.
  • Structural Complexity: The unique structure of this compound, featuring a benzylpiperidin-1-ium moiety, contributes to its pharmacological profile. The presence of multiple phenyl groups enhances its interaction with biological targets.
  • Ionization: The inclusion of the benzyl group in the piperidine structure leads to ionization in physiological conditions, which can affect the compound's solubility and permeability in biological systems.
  • Potential in Drug Development: This compound could serve as a lead structure for the design of new drugs aimed at treating neurodegenerative diseases, given the importance of piperidine derivatives in neurological therapies.
  • Multi-Dimensional Applications: Beyond medicinal chemistry, compounds like this one can be explored in materials science and organic synthesis, showcasing the versatility of piperidine derivatives in various scientific fields.

As researchers continue to explore the myriad possibilities of such complex chemicals, the future of similar compounds presents opportunities for groundbreaking advances in medicine and technology. Let us not forget the eloquent words of renowned chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." This sentiment rings true as scientists innovate and experiment with compounds like (3S)-3-(1-benzylpiperidin-1-ium-4-yl)-3-phenyl-piperidine-2,6-dione;chloride.

Synonyms
Tremblex
(S)-3-Phenyl-1'-(phenylmethyl)(3,4'-bipiperidine)-2,6-dione monohydrochloride
Dexbenzetimide hydrochloride
UNII-B987A3XX7D
Dextrobenzetimide hydrochloride
EINECS 244-633-2
(+)-2-(1-Benzyl-4-piperidyl)-2-phenylglutarimide hydrochloride
(+)-1-Benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)piperidine hydrochloride
(+)-3-(1-Benzyl-4-piperidyl)-3-phenylpiperidine-2,6-dione hydrochloride
(3,4'-BIPIPERIDINE)-2,6-DIONE, 3-PHENYL-1'-(PHENYLMETHYL)-, HYDROCHLORIDE, (S)-
(S)-3-Phenyl-1'-(phenylmethyl)-(3,4'-bipiperidine)-2,6-dione hydrochloride