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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
(3S)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
State
State
At room temperature, corticosterone is a solid. It is typically processed and handled in its solid form, often as a powder for laboratory and pharmaceutical applications. It should be stored in a cool, dry place, protected from direct sunlight and moisture.
Melting point (Celsius)
184.00
Melting point (Kelvin)
457.15
Boiling point (Celsius)
403.00
Boiling point (Kelvin)
676.15
General information
Molecular weight
346.47g/mol
Molar mass
346.4680g/mol
Density
1.2000g/cm3
Appearence
Corticosterone appears as a white crystalline powder. It is often supplied in a powdered form and is relatively stable under standard conditions. The crystals can be characterized by standard crystallography techniques, having a typical crystalline structure of steroids.
Comment on solubility

Solubility of (3S)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

The solubility of this complex organic compound is influenced by several factors, primarily its molecular structure and functional groups. Here are some key considerations regarding its solubility:

  • Polar vs. Nonpolar Characteristics: The presence of hydroxyl groups (-OH) in the structure can impart some polar characteristics, suggesting that the compound may exhibit moderate solubility in polar solvents like water.
  • Hydrophobic Regions: Given the extensive hydrocarbon framework, the majority of the molecule is likely nonpolar, which can limit its solubility in polar solvents while enhancing its solubility in organic solvents such as ethanol or chloroform.
  • Temperature Influence: Solubility may vary significantly with temperature; typically, as temperature increases, so does solubility in most solvents, although exceptions may exist based on specific interactions.

In conclusion, while the solubility of (3S)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one may be reasonable in organic solvents, its solubility profile is likely to be complex and influenced by solvent type, temperature, and molecular interactions. Understanding these factors is crucial for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about (3S)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

This compound, a fascinating member of the class of steroids, holds significant importance in various fields, particularly in biochemistry and pharmacology. Here are some engaging details that showcase its significance:

  • Structural Complexity: The compound is characterized by a complex ring structure, featuring multiple fused rings that contribute to its unique chemical behavior and biological activity.
  • Hydroxyl Groups: The presence of hydroxyl groups at specific positions not only enhances solubility and reactivity but also plays a crucial role in biological interactions.
  • Potential Biological Activity: Compounds like this often exhibit various biological activities, including but not limited to anti-inflammatory, anticancer, and hormone-like effects, making them of interest in drug discovery.
  • Natural Occurrence: Structures similar to this compound can be found in various natural steroids, suggesting evolutionary significance and implications in natural pathways in organisms.
  • Research Applications: Many compounds of this class are used as references in research to explore mechanisms of action in cellular processes, which could lead to breakthroughs in therapeutic applications.

Understanding compounds like (3S)-3,11-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one enriches our comprehension of chemical interactions and underscores the potential benefits they hold for human health.

In the words of a notable chemist, “The beauty of chemistry lies not only in its complexity but also in its ability to impact health, industry, and the environment.”
This compound exemplifies that notion with its intricate design and potential implications.