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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
[(3S,10S,13R,14S)-10-formyl-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
State
State

At room temperature, corticosterone is in a solid state, specifically in a crystalline form.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
570.50
Boiling point (Kelvin)
843.65
General information
Molecular weight
346.42g/mol
Molar mass
346.4210g/mol
Density
1.3400g/cm3
Appearence

Corticosterone is a white crystalline powder. It lacks color and is usually found in a purified solid form.

Comment on solubility

Solubility of the Compound

The solubility of the compound [(3S,10S,13R,14S)-10-formyl-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate can be quite complex due to its intricate structure. Several factors influence its solubility:

  • Polarity: The presence of functional groups such as the formyl and hydroxy groups contribute to increased polarity, which may enhance solubility in polar solvents.
  • Steric Hindrance: Due to the bulky dodecahydrocyclopenta[a]phenanthrene core, there may be some steric hindrance that could affect solubility within various solvents.
  • Interaction with Solvents: Solubility is also determined by how well the compound can interact with solvent molecules. In *non-polar solvents*, the solubility might be limited, while *polar solvents* could potentially dissolve the compound better.

It can be said that the solubility varies significantly with the specific solvent used, and it is advisable to conduct empirical tests to determine precise solubility data. Factors such as temperature and pH can also play crucial roles in this context. As one researcher put it, "To understand solubility, one must also understand the dance between solvent and solute."

In conclusion, while the solubility of this compound is influenced by its considerable structural complexity, a thorough investigation can provide valuable insights into its behavior in various environments.

Interesting facts

Interesting Facts about the Compound

This fascinating compound, known for its complex structure, brings together elements that are both intriguing and vital in the field of organic chemistry. Here are some highlights:

  • Structural Complexity: The compound features multiple chiral centers, specifically at the 3, 10, 13, and 14 positions, which contributes to its unique three-dimensional configuration. Chiral molecules like this one are critical in pharmaceutical development as they can exhibit different biological activities based on their orientation.
  • Functional Groups: The presence of a formyl group (−CHO) and a hydroxyl group (−OH) indicates that this compound may possess interesting reactivity, making it a potential candidate for further chemical transformations or reactions.
  • Natural Product Potential: Given its elaborate structure, this compound may be related to natural products found in plants or microorganisms. Many synthetic analogs inspired by nature exhibit unique pharmacological properties, and this compound could follow suit.
  • Applications in Medicine: Compounds featuring furan-3-yl groups have been explored for a variety of bioactivities, including anti-cancer and anti-inflammatory effects. This opens up possibilities for research into the therapeutic use of this compound or its derivatives.
  • Research Opportunities: The unique structural characteristics present numerous opportunities for further research in both synthesis and application, encouraging students and scientists alike to explore its potential uses.

As chemical researchers continue to unravel the intricacies of such compounds, it is important to remember that each unique structure could hold the key to significant discoveries in medicine and materials science. The ongoing study of this compound exemplifies the boundless opportunities within the realm of chemistry.