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Corticosteroid

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Identification
Molecular formula
C21H28O5
CAS number
124-94-7
IUPAC name
(3S,10S,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
State
State

At room temperature, the compound is typically in a solid state, existing as white to off-white crystals.

Melting point (Celsius)
221.00
Melting point (Kelvin)
494.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
360.45g/mol
Molar mass
360.4500g/mol
Density
1.2000g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of (3S,10S,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

The solubility of this complex organic compound is influenced by various factors, which can be summarized as follows:

  • Polar vs. Nonpolar Characteristics: This compound contains multiple -OH groups, making it generally more polar. Polar compounds tend to be soluble in polar solvents such as water.
  • Hydroxyl Groups: The presence of hydroxyl (–OH) functional groups not only enhances polarity but also allows for potential hydrogen bonding, which can significantly affect solubility.
  • Conformational Structure: The three-dimensional structure of the molecule, including its stereochemistry, can hinder or promote solubility depending on how well it can interact with solvent molecules.
  • Solvent Compatibility: Solubility will vary greatly depending on the solvent used. For instance, while it may show good solubility in alcohols and dimethyl sulfoxide (DMSO), its solubility in hydrocarbons or nonpolar solvents may be limited.

To summarize, while the presence of hydroxyl groups suggests potential solubility in polar solvents, the overall solubility of (3S,10S,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde will ultimately depend on its interactions with specific solvents. As stated in the adage "like dissolves like", understanding the polarity of both solute and solvent is key to predicting solubility behavior.

Interesting facts

Interesting Facts about (3S,10S,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(6-oxopyran-3-yl)-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

This complex organic compound showcases a fascinating blend of structural intricacies and biological relevance, making it a significant subject of study in the field of chemistry. Here are some interesting facts about this elusive molecule:

  • Structural Complexity: The compound features multiple stereocenters, including four chiral centers. This chirality is crucial as it often determines the compound's interaction with biological systems, such as enzymes and receptors.
  • Biological Relevance: Compounds structured like this one are often found in natural products, particularly in the realm of pharmaceuticals. They may play roles in specific biological activities, including anti-inflammatory and anti-cancer properties.
  • Oxopyran Moiety: The 6-oxopyran-3-yl group present in the structure is known for its involvement in various biochemical processes, adding to the compound's functional versatility.
  • Synthetic Pathways: The synthesis of such complex molecules often requires innovative synthetic techniques, often involving multiple reaction steps, protecting group chemistry, and stereochemical considerations.
  • Research Potential: Compounds with such intricate structures are continuously being researched for their potential therapeutic applications. A better understanding of their properties and mechanisms can lead to novel drug discoveries.

In summary, this compound exemplifies both the beauty of chemical diversity and the challenges chemists face in elucidating its properties and potential applications. As research continues, the understanding of similar compounds may unlock new avenues in pharmacology and organic chemistry.