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Bryostatin 1

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Identification
Molecular formula
C47H68O17
CAS number
83314-20-9
IUPAC name
(3S,5R,10R,13R,14S,17R)-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2S,5S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
State
State

At room temperature, Bryostatin 1 is typically found as a solid in its purified form.

Melting point (Celsius)
0.00
Melting point (Kelvin)
0.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
905.04g/mol
Molar mass
905.0380g/mol
Density
1.1800g/cm3
Appearence

Bryostatin 1 is typically a white to off-white powder. It is a macrocyclic lactone that can sometimes present in a slightly amorphous form.

Comment on solubility

Solubility of (3S,5R,10R,13R,14S,17R)-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2S,5S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

The solubility of this compound, which possesses a complex structure with multiple functional groups, can vary significantly depending on its environment. Key factors influencing its solubility include:

  • Polarity: The presence of hydroxyl groups (-OH) tends to enhance solubility in polar solvents like water.
  • Hydrophobic regions: The hydrocarbon backbone and furan ring may impart hydrophobic characteristics, potentially decreasing solubility in polar solvents.
  • pH Levels: The solubility can also change with pH, particularly for compounds containing acidic or basic functional groups.
  • Temperature: Higher temperatures generally increase solubility for solids in liquids, though this may not be a universal rule.

As a result, one might encounter the statement, "The solubility of complex organic compounds is often a balance of their hydrophilic and hydrophobic interactions." Analytical methods can be utilized to determine precise solubility data, which is crucial for understanding the compound's behavior in various applications.

In summary, the solubility of (3S,5R,10R,13R,14S,17R)-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2S,5S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde is intricate and must be approached with care and detailed experimentation.

Interesting facts

Exploring the Unique Properties of (3S,5R,10R,13R,14S,17R)-14-Hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-3-[(2S,5S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

This complex organic compound is a fascinating example of the intricate structures found in natural products. Here are some engaging aspects to consider:

  • Stereochemistry: The strict stereochemical configuration indicated by the descriptors (e.g., 3S, 5R) highlights the compound's spatial arrangement, which is crucial for its biological activity. Stereoisomers can behave very differently in biological systems.
  • Functional groups: The presence of hydroxyl (-OH) groups and a furan moiety suggests potential applications in medicinal chemistry, particularly in developing pharmaceuticals.
  • Biological activity: Compounds with similar structures often exhibit interesting biological properties, including antioxidant, anti-inflammatory, and anticancer activities, making this compound a potential candidate for further research.
  • Naturally Derived: Many compounds with such complex structures are derived from natural sources, including plants and fungi, which underscores the significance of chemical diversity in nature.

As said by the renowned scientist Linus Pauling, "The nature of the chemical bond is the most important factor in the behavior of matter." This compound exemplifies how molecular structure profoundly influences the properties and applications of substances.

The intricate interactions of this molecular system can inspire future studies, paving the way for innovative applications in various scientific fields. As exciting as it is complex, this compound stands as a testament to the beauty of chemistry.