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Cortisone acetate

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Identification
Molecular formula
C23H30O6
CAS number
50-04-4
IUPAC name
[(3S,5R,10S,13R,14S,16S,17R)-14,16-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate
State
State

Cortisone acetate is a solid at room temperature.

Melting point (Celsius)
220.50
Melting point (Kelvin)
493.65
Boiling point (Celsius)
395.70
Boiling point (Kelvin)
668.85
General information
Molecular weight
402.48g/mol
Molar mass
402.4820g/mol
Density
1.3100g/cm3
Appearence

Cortisone acetate appears as a white or slightly creamy white crystalline powder. It is odorless or may have a slight, characteristic odor.

Comment on solubility

Solubility of the Compound

The solubility of the compound [(3S,5R,10S,13R,14S,16S,17R)-14,16-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate is a complex topic, largely dependent on several factors such as polarity, molecular structure, and the presence of functional groups. Below are some key points regarding its solubility:

  • Polarity: The presence of hydroxyl groups (-OH) in the structure suggests that the compound may exhibit some degree of solubility in polar solvents like water. However, the extensive hydrocarbon backbone may hinder complete solubility.
  • Functional Groups: The acetate functional group may enhance the solubility in organic solvents. Acetates generally soluble in organic solvents due to their polar nature.
  • Molecular Weight: The large molecular weight of this compound could contribute to lower solubility overall, as larger molecules tend to have more complex intermolecular interactions, often leading to reduced solubility in solvents.

In summary, the solubility of this compound is likely influenced by a delicate balance of its polar and non-polar characteristics. Experimental data would be essential to accurately determine its solubility in various solvents. As with many organic compounds, one can expect differing solubility profiles across a range of solvents, potentially leading to a fascinating understanding of its behavior in various chemical environments.

Interesting facts

Interesting Facts about Acetate of 14,16-Dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene

This complex compound belongs to a class of organic molecules known for their diverse biological activities. Here are some captivating insights:

  • Biosynthesis: The structure features a tetradecahydrocyclopenta[a]phenanthrene skeleton, characteristic of many steroid-like compounds, which are often involved in biochemical pathways.

  • Natural Origins: Compounds with similar configurations are frequently found in natural sources, such as plants, suggesting a potential role in natural product chemistry.

  • Potential Applications: The hydroxyl and oxo functional groups in this compound may indicate potential as pharmaceuticals or therapeutic agents, especially in research related to anti-cancer or anti-inflammatory properties.

  • Chirality: The specific configuration (S and R stereochemistry) of the compound is significant, as chirality can influence the biological activity and interaction of the molecule within living organisms.

  • Functional Group Importance: The presence of both hydroxyl and acetyl groups makes this compound particularly interesting for chemical reactivity; this opens up possibilities for further derivatization and study.

As scientists continue to explore the roles of such complex organic molecules, the intricate relationship between structure and function becomes increasingly evident. Each compound tells a story of evolution, adaptation, and potential innovation within the realms of chemistry and biology.

Synonyms
3-Monoacetylgitoxigenin
[(3S,5R,10S,13R,14S,16S,17R)-14,16-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate
BRN 0061015
5-beta-CARD-20(22)-ENOLIDE, 3-beta,14,16-beta-TRIHYDROXY-, 3-ACETATE
DTXSID90909816
3-(Acetyloxy)-14,16-dihydroxycard-20(22)-enolide