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Cortisol acetate

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Identification
Molecular formula
C26H36O6
CAS number
50-03-3
IUPAC name
[(3S,5R,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] acetate
State
State

At room temperature, cortisol acetate is a solid substance. It is stable but should be stored in a sealed container to protect it from moisture and air.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
555.00
Boiling point (Kelvin)
828.15
General information
Molecular weight
446.57g/mol
Molar mass
446.5200g/mol
Density
1.2000g/cm3
Appearence

Cortisol acetate usually appears as a white or almost white powder. It is typically odorless and may be available in crystalline form. Due to its steroidal structure, it has a complex, polycyclic appearance under a microscope.

Comment on solubility

Solubility of [(3S,5R,10S,13R,14S,16S,17R)-3,14-dihydroxy-10,13-dimethyl-17-(6-oxopyran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-16-yl] acetate

The solubility of this complex compound can vary significantly based on several factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups suggests that the compound may have some degree of polarity, potentially increasing its solubility in polar solvents such as water.
  • Hydrophobic Regions: The large hydrocarbon portions of the molecular structure can lead to solubility challenges in aqueous environments but may promote better solubility in organic solvents.
  • Functional Groups: The ester functional group (-O-C(=O)-) may also enhance its solubility in specific organic solvents due to its ability to interact favorably with various solvation environments.

Furthermore, it is essential to consider:

  • Temperature Effects: Increased temperatures can improve solubility for many compounds, allowing for more effective intermolecular interactions.
  • pH Levels: The solubility may also be affected by pH levels; for example, more acidic or basic conditions can influence the ionization state of the functional groups.

Overall, the solubility nature of this acetate compound is expected to exhibit a balance between its hydrophilic and hydrophobic characteristics, thus making it a potential candidate for study in various solvent systems.

Interesting facts

Interesting Facts About the Compound

This compound is a fascinating example of complex organic molecules with significant biological implications. It belongs to a class of steroids, noted for their multi-ring structure that plays a crucial role in various biochemical processes.

Chemical Structure and Functionality

The intricate structure of this compound showcases:

  • Hydroxyl Groups: The presence of two hydroxyl (–OH) groups suggests its potential as a secondary metabolite, enhancing its reactivity and interaction with biological systems.
  • Dimethyl Substituents: The dimethyl groups could influence molecular conformation, thereby affecting how the compound interacts with enzymes and receptors in living organisms.
  • Oxygenated Functional Groups: The attachment of a 6-oxopyran-3-yl moiety might contribute to its pharmacological properties, opening doors to discussion on drug design and targeting mechanisms.

Biological Significance

This compound could potentially be involved in:

  • Hormonal Activity: Given its steroidal nature, it might mimic or inhibit certain hormones, impacting growth and development in various organisms.
  • Medicinal Applications: With ongoing research in pharmaceutical chemistry, compounds of this nature are often investigated for anti-inflammatory and anticancer properties.

Research and Development

Chemists and pharmacologists are particularly interested in such compounds for several reasons:

  • Inspiration for Synthesis: Its complex structure can serve as inspiration for synthetic chemists striving to develop new compounds with unique properties.
  • Model Studies: It may be used as a model for examining interactions in biological systems or for exploring the mechanisms of drug action.

In summary, the study of this compound not only enlightens our understanding of organic chemistry but also propels advancements in medicinal chemistry. As we delve deeper into the complexities of such compounds, we uncover the multifaceted relationships between structure and biological function.

Synonyms
SCHEMBL865714