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Testosterone

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Identification
Molecular formula
C19H28O2
CAS number
58-22-0
IUPAC name
(3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one
State
State
At room temperature, testosterone is a solid. It exists as a crystalline powder and is practically insoluble in water.
Melting point (Celsius)
153.00
Melting point (Kelvin)
426.00
Boiling point (Celsius)
381.20
Boiling point (Kelvin)
654.40
General information
Molecular weight
288.42g/mol
Molar mass
288.4240g/mol
Density
1.1253g/cm3
Appearence

Testosterone is a white to off-white crystalline powder. It is odorless and stable in air, but it may degrade under prolonged exposure to light.

Comment on solubility

Solubility of (3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

The solubility of (3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one can be quite complex due to its intricate structure and molecular characteristics. To better understand its solubility, consider the following points:

  • Polarity: The hydroxyl group (-OH) contributes to the compound's polarity, which typically enhances solubility in polar solvents such as water.
  • Hydrophobic Regions: The extensive hydrophobic hydrocarbon framework may limit its solubility in polar solvents, favoring solubility in organic solvents such as ethanol or chloroform.
  • Effects of Temperature: Solubility can also be temperature-dependent; generally, heating solvents can lead to increased solubility.
  • Concentration Factors: At higher concentrations, there could be changes in solubility due to solute-solvent interactions, such as aggregation.

In summary, while the hydroxyl group may enable some degree of solubility in aqueous environments, the overall solubility of this compound is likely to be restricted in comparison to more simple or highly polar compounds. Therefore, when working with this compound, it is essential to choose the solvent carefully based on the intended application.

Interesting facts

Interesting Facts about (3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one

This fascinating compound, often referred to in the scientific community for its complex structure, is a member of the steroid family, which includes a wide range of biologically significant molecules. Its unique stereochemistry, denoted by the (3S,5S) configuration, plays a critical role in its interaction with biological systems. Here are some intriguing aspects of this compound:

  • Biosynthesis: Being a steroid derivative, this compound can be synthesized through various pathways in biological systems, highlighting the importance of both natural and laboratory synthesis methods in developing similar compounds.
  • Potential Biological Activity: Compounds of this class are often studied for their hormonal activities and could potentially exhibit roles in regulating various physiological processes or serve as precursors for the synthesis of hormones.
  • Structural Complexity: The tetradecahydro structure indicates a high degree of saturation, which contributes to the stability and reactivity of the molecule. This complexity affords potential applications in medicinal chemistry.
  • Research Interest: The compound has piqued the interest of researchers exploring its applications in pharmaceuticals, particularly in drug design and development targeting hormonal pathways.

As the field of chemistry continues to progress, compounds like (3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one remind us of the vast array of molecular architectures that can potentially lead to groundbreaking discoveries and innovations in health and medicine.

Synonyms
Androstan-17-one, 3-hydroxy-, (3.beta.,5.alpha.)-
Androstan-17-one, 3-hydroxy-, (3beta,5alpha)-
Androstan-17-one, 3-hydroxy-, (3beta,5alpha)-(9CI)
3-Epiandrosterone
3-.beta.Hydroxyandrostan-17-one
5.alpha.-Androstan-3.beta.-ol-17-one
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