Skip to main content

Corticosterone

ADVERTISEMENT
Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
(3S,5S,10R,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
State
State

Corticosterone is typically a solid at room temperature. It is in the form of a dry powder, making it amenable for laboratory handling and storage under appropriate conditions.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.00
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.00
General information
Molecular weight
346.45g/mol
Molar mass
346.4440g/mol
Density
1.1000g/cm3
Appearence

Corticosterone appears as a white crystalline powder. It is usually odorless and has a bitter taste. It is sensitive to light, and hygroscopic in nature, which implies it can absorb moisture from the air.

Comment on solubility

Solubility of (3S,5S,10R,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

The solubility of complex organic compounds like (3S,5S,10R,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde can be influenced by several factors:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents like water. However, the overall structure of the compound may limit its solubility.
  • Molecular Size: Larger molecules generally exhibit lower solubility due to decreased interaction with solvent molecules. This compound, with its multiple ring structures, may present challenges in solubility.
  • Interactions: The interactions between the solute (the compound in question) and solvent molecules, such as hydrogen bonding, can affect solubility. The effectiveness of these interactions varies from one solvent to another.
  • Functional Groups: The specific functional groups present can play a significant role—here, the furan and hydroxyl groups can contribute to needle-like solubility in certain solvents when combined.

In summary, while certain structural components may indicate potential solubility in specific solvents, the unique characteristics of this compound suggest that its solubility may be limited. Thus, experimental determination in various solvents is essential for accurate assessment.

Interesting facts

Interesting Facts about (3S,5S,10R,13R,14S,17R)-3,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde

This compound, with its intricate naming, belongs to a class of organic molecules known for their complexity and diverse structures. Here are some engaging insights:

  • Natural Product Chemistry: This compound's structure suggests it may be derived from or inspired by natural products, which often exhibit diverse biological activities.
  • Potential Therapeutics: The presence of hydroxyl and carbonyl functional groups in its structure may indicate potential in pharmaceutical applications, particularly in designing drugs that interact with biological receptors.
  • Stereochemistry: The specific stereochemical descriptors (S and R) signify multiple chiral centers in this molecule, making it an interesting subject of study in stereochemistry and its effects on biological activity.
  • Applications in Organic Synthesis: The complex structure of this compound showcases the challenges and techniques in synthesizing large organic molecules, which is a critical area of focus in synthetic organic chemistry.

As a scientific exploration point, the compound serves as a reminder of the vast diversity in chemical compounds and the intricate relationships between their structure and function. In the words of renowned chemist Linus Pauling, "The best way to get a good idea is to have a lot of ideas." This principle certainly applies in the study of complex molecules like this one!


In summary, the study of this compound not only touches upon synthetic methodologies but also paves the way for potential future research in drug discovery and the understanding of natural products. Its unique features significantly enrich the conversations around modern chemistry and its applications.

Synonyms
NS00094656