Skip to main content

Pyripyropene A

ADVERTISEMENT
Identification
Molecular formula
C29H33NO6
CAS number
164319-12-0
IUPAC name
[(3S,5S,10S,13R,14S,17R)-10-formyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] pyridine-3-carboxylate
State
State

At room temperature, Pyripyropene A is in a solid state and is stable under normal conditions. Its stability makes it suitable for various applications and studies.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
106.00
Boiling point (Kelvin)
379.15
General information
Molecular weight
496.59g/mol
Molar mass
496.5150g/mol
Density
1.3457g/cm3
Appearence

Pyripyropene A is a light yellow crystalline solid. It usually appears as finely powdered crystals.

Comment on solubility

Solubility of the Compound

The solubility of the given compound, [(3S,5S,10S,13R,14S,17R)-10-formyl-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] pyridine-3-carboxylate, can be analyzed through several factors:

  • Polarity: The presence of multiple functional groups such as hydroxyl (-OH) and carbonyl (C=O) enhances its polarity, which can facilitate solubility in polar solvents like water.
  • Hydrogen Bonding: Due to hydroxyl groups, the compound has the potential to form hydrogen bonds with solvents, contributing to increased solubility in polar environments.
  • Structural Complexity: Its intricate structure may hinder solubility in nonpolar solvents, reducing compatibility with nonpolar organic compounds.
  • Solvent Interactions: Interaction with various solvents can lead to different solubility profiles. It is likely to be more soluble in methanol and ethanol compared to hexane or chloroform.

As a general rule, "like dissolves like," so choosing a solvent that matches the compound's properties is crucial for maximizing solubility.

Overall, while the compound may exhibit moderate solubility in polar solvents, its complex structure will require careful consideration in practical applications.

Interesting facts

Interesting Facts about the Compound

This compound features a sophisticated structure that is not only intriguing from a chemical standpoint but also rich in potential applications. Here are some fascinating aspects of it:

  • Chiral Centers: This molecule contains multiple chiral centers, specifically at the 3, 5, 10, 13, 14, and 17 positions. This chirality may result in different stereoisomers, each of which could exhibit unique biological activities.
  • Functional Groups: The compound exhibits several functional groups, such as aldehyde, hydroxyl, and furan, which are known for their diverse reactivity. Each of these functional groups can participate in a variety of chemical reactions, making this compound a versatile candidate for synthetic chemistry.
  • Natural Product Inspiration: Many complex organic compounds, particularly those found in nature, often serve as models for drug development. This compound's intricate structure suggests that it could be similar to naturally occurring steroids or other alkaloids, which are pivotal in medicinal chemistry.
  • Potential Applications: Due to its unique composition, the compound might hold promise in pharmaceuticals. It may serve as a precursor in the synthesis of drugs targeting specific diseases or could even act as a lead compound for further optimizations in drug discovery.
  • Research Opportunities: The study of this compound can pave the way for extensive research into its synthesis, potential pharmacological properties, and mechanisms of action, contributing to a deeper understanding of structure-activity relationships in similar compounds.

As the field of medicinal chemistry continues to evolve, compounds like this one play a crucial role in the quest for novel therapeutics. Their complex structures challenge researchers to devise innovative approaches for synthesis and modification, highlighting the beauty and complexity of organic chemistry.

Synonyms
Go 2616
Strophanthidin-3-nicotinate
BRN 0070085
Nicotinic acid, ester with strophanthidin
5-beta-Card-20(22)-enolide, 19-oxo-3-beta,5,14-trihydroxy-, 3-nicotinate
(3-beta,5-beta)-5,14-Dihydroxy-19-oxo-3-((3-pyridinylcarbonyl)oxy)card-20(22)-enolide
Card-20(22)-enolide, 5,14-dihydroxy-19-oxo-3-((3-pyridinylcarbonyl)oxy)-, (3-beta,5-beta)-
21515-43-5
4-22-00-00385 (Beilstein Handbook Reference)
RefChem:382323
DTXSID90944126
5,14-Dihydroxy-19-oxo-3-[(pyridine-3-carbonyl)oxy]card-20(22)-enolide